Assistant Professor Bree Aldridge has received a 2013 National Institutes of Health Director’s New Innovator Award. Aldridge is an assistant professor in molecular biology and microbiology at Tufts University School of Medicine, a member of the Molecular Microbiology and Immunology program faculties at the Sackler School of Graduate Biomedical Sciences at Tufts, and adjunct assistant professor in biomedical engineering. She has been awarded a five-year, $1.5 million grant for her research focused on improving drug treatments for tuberculosis.
Aldridge’s research addresses a major obstacle in controlling tuberculosis, which is the lengthy multi-drug therapy currently required to effectively cure the disease. Due to the prolonged treatment, adherence to the drug therapy can be difficult. In addition, when these drugs are misused or mismanaged, multi-drug resistance can develop. To improve health outcomes for patients, and reduce the emergence of drug-resistant strains of the disease, she hopes to shorten and simplify treatments for tuberculosis. The Aldridge lab includes a multidisciplinary team of researchers who combine molecular approaches with mathematical modeling to study the bacterium that causes tuberculosis.