Engineering faculty Professor Sameer Sonkusale and Associate Professor Qiaobing Xu, working with Assistant Professor Jimmy Crott from the Human Nutrition Research Center on Aging, have received a $1 million grant from the Office of Naval Research to build biomedical microdevices to investigate the gut microbiome.
Current studies of the gut microbiome rely on the metabolic and genomic analysis of fecal matter. That analysis fails to identify which areas of the large or small intestine are colonized by bacterial species, and how those bacterial species interact with one another and with the host. This research project seeks to sample the microbiome at different locations in the gut to obtain a spatial distribution profile. Sonkusale, Xu, and Crott have proposed the use of a biocompatible lab-on-a-pill with integrated sensor, energy source, and electronics, to carry out that sampling.