Shuchin Aeron, assistant professor of electrical and computer engineering, has received a five-year $530,000 NSF early career award for his work advancing multidimensional data science via new algebraic models and algorithms. The outcome of this research will re-invigorate interest from the applied mathematics and signal processing communities in using tools from linear and multilinear algebra that are not currently exploited.
The research involves collaboration with Tufts Department of Mathematics, Tufts Department of Neuroscience and Tufts Interactive Learning and Collaboration Environment (InterLACE) program, Brigham and Women’s Hospital, and AT&T research.
Widespread use of electric vehicles could offer relief from pollution, says Assistant Professor of Mechanical Engineering Iryna Zenyuk, and hydrogen fuel cells present the option for a cleaner, more efficient power source. However, the water byproduct created inside a hydrogen fuel cell compromises the cell’s efficiency.
Their research has been published in Scientific Reports. In addition to Kaplan and Omenetto, authors include first author Benedetto Marelli, Ph.D., formerly a post-doctoral associate in the Omenetto laboratory and now at MIT; and Mark A. Brenckle, Ph.D., former research assistant in the Omenetto Laboratory, now at Columbia University.
Encapsulating blood samples in silk protein extracted from silk worm cocoons protected biomarkers effectively, even at high temperatures. (Courtesy Tufts Silk Lab)
A team of Tufts University researchers, including Professors David Kaplan and Fiorenzo Omenetto, have stabilized blood samples without refrigeration, by using air-dried silk protein to encapsulate the samples. The technique has implications for clinical care and research that require analysis of biofluids like blood, and could open up new testing options for currently underserved populations.
The research was published in the Proceedings of the National Academy of Sciences of the United States of America. In addition to Kaplan and Omenetto, authors include co-first author Jonathan Kluge, Ph.D., former postdoctoral associate in the Kaplan lab; Adrian B. Li, Ph.D., scientist at Vaxess Laboratories and a former doctoral student in Tufts’ Department of Chemical and Biological Engineering; Brooke Kahn, B.S., research associate at Cocoon Biotech and former intern in the Kaplan laboratory; and Dominique S. Michaud, Sc.D., Tufts University School of Medicine.
Associate Professor Luis Dorfmann contributed to research that built a mathematical model to explain the dynamics of the quick release of a chameleon’s tongue. The model could potentially have applications in designing elastic materials. Read the article from BBC News and the full paper as published in the Proceedings of the Royal Society of London A.
Massachusetts Governor Charlie Baker announced $3 million in state support of the Cluster for Advanced Nanomanufacturing of Smart Sensors and Materials (ANSSeM) — a consortium of Massachusetts businesses and universities led by Northeastern University that includes Tufts University School of Engineering and University of Massachusetts Boston. Associate Professor Sameer Sonkusale in the Department of Electrical and Computer Engineering and Professor Igor Sokolov in the Department of Mechanical Engineering will purchase equipment for developing nanoscale sensors and for measuring nanomechanical properties, respectively.
“In general, robots should never perform illegal actions, nor should they perform legal actions that are not desirable. Hence, they will need representations of laws, moral norms and even etiquette in order to be able to determine whether the outcomes of an instructed action, or even the action itself, might be in violation of those principles,” Scheutz writes.
Assistant Professor Erica Kemmerling, Mechanical Engineering
Assistant Professor Erica Kemmerling writes for The Conversation about fabricating physical models to study how cardiovascular devices affect blood flow. Now 3D printing technology is advanced enough to build realistic models of human blood vessels, and pulsatile-flow pumps can drive flow through these vessels to mimic the heart’s pumping. Since the vessel models are synthetic, there are no ethical issues associated with damaging them to take flow measurements.
Professor Dan Kuchma, Civil and Environmental Engineering
Professor Dan Kuchma discussed offshore installations and siting as part of the 2016 Wind Energy Research Workshop, sponsored by National Science Foundation, Massachusetts Clean Energy Center, Tufts University, and UMass Lowell which was held March 15-17.
A central challenge to the development of protein-based therapeutics is the inefficiency of delivering proteins across the cell membrane. Assistant Professor Qiaobing Xu is the co-author on a paper in the Proceedings of the National Academy of Sciences that demonstrated delivery of genome-editing proteins into cultured human cells with 70% efficacy comparable with or exceeding other commercially available systems. Xu and Ming Wang, postdoctoral scholar and first author, and collaborators also demonstrated that these lipids are effective for functional protein delivery for murine gene recombination in vivo. Xu’s lab will now pursue studies to better assess toxicity.