Innovation

Hypofractionated radiation therapy combined with the ONCEPT canine melanoma vaccine for canine oral melanoma

The Veterinary Radiation Therapy Oncology Group consists of a group of board-certified radiation oncologists across the nation dedicated to cooperative clinical trials to improve the survival of animals with cancer. The team at Tufts’ Foster Hospital for Small Animals is part of this consortium and is currently enrolling patients.  This organization is currently conducting an independent study to evaluate the treatment of canine oral malignant melanoma with coarse-fraction radiotherapy (8 Gy for 4 weekly fractions) in combination with the ONCEPT™ melanoma vaccine. Data for three treatment groups (concurrent radiation therapy and vaccine; radiation therapy alone; vaccine alone) will be collected.  Given that the study is not funded, treatment selection will be based on owners preference.  The primary objective of this study is to compare tumor progression between the treatment groups with a secondary objective of evaluating overall survival time. Continue reading