Hypofractionated radiation therapy combined with the ONCEPT™caninemelanoma vaccine for canine oral melanoma
The Veterinary Radiation Therapy Oncology Group consists of a group of board-certified radiation oncologists across the nation dedicated to cooperative clinical trials to improve the survival of animals with cancer. The team at Tufts’ Foster Hospital for Small Animals is part of this consortium and is currently enrolling patients. This organization is currently conducting an independent study to evaluate the treatment of canine oral malignant melanoma with coarse-fraction radiotherapy (8 Gy for 4 weekly fractions) in combination with the ONCEPT™ melanoma vaccine. Data for three treatment groups (concurrent radiation therapy and vaccine; radiation therapy alone; vaccine alone) will be collected. Given that the study is not funded, treatment selection will be based on owners preference. The primary objective of this study is to compare tumor progression between the treatment groups with a secondary objective of evaluating overall survival time. Continue reading →
The clinical oncology service is comprised of veterinary oncologists, residents and technicians that work together as a team. The oncology service works closely with the surgery service, which has expertise in surgical oncology, as well as with pathology, diagnostic imaging, interventional radiology, and the pain clinic. Through the collaboration with these and other specialty services throughout the hospital, we are able to offer a broad range of options for owners of companion animals with cancer.
As a member of the National Cancer institute’s Comparative Oncology Trials Consortium, as well as through independent studies and collaboration with other veterinary and biomedical institutions, the oncology service is able to offer investigational therapies in addition to conventional treatment.
The oncology service boasts a 6 MV Siemens linear accelerator with 2-16 MeV electrons, a multileaf collimator, and intensity-modulated radiation therapy (IMRT) capabilities. In addition, strontium 90 plesiotherapy is offered, allowing for wide breadth of radiation therapy options. Continue reading →