Issued U.S. Patents

The following 24 U.S. patents were issued to Tufts University between January 1, 2013, and September 30, 2013:

Methods and systems for multi-antibody therapies
Inventors: Charles B. Shoemaker and Jean Mukherjee
U.S. patent 8,349,326, issued January 8, 2013

Methods for stepwise deposition of silk fibroin coatings
Inventors: David L. Kaplan and Xianyan Wang
U.S. patent 8,354,501, issued January 15, 2013

Wound healing peptides and methods of use thereof
Inventor: Ira M. Herman      
U.S. patent 8,357,655, issued January 22, 2013

Silk fibroin materials and use thereof
Inventors: David L. Kaplan, Rina Nazarov, Gordana Vunjak-Novakovic and Lorenz Meinel
U.S. patent 8,361,617, issued January 29, 2013, to Tufts University and Massachusetts Institute of Technology

Catalyst having metal in reduced quantity and reduced cluster size
Inventors: Maria Flytzani-Stephanopoulos, Howard M. Saltsburg and Qi Fu
U.S. patent 8,377,841, issued February 19, 2013

Non-flushing niacin analogues, and methods of use thereof
Inventors: William W. Bachovchin and Hung-Sen Lai
U.S. patent 8,377,971, issued February 19, 2013

Treating catalysts
Inventors: Maria Flytzani-Stephanopoulos and Xiaoyan She
U.S. patent 8,394,736, issued March 12, 2013

Methods for treating autoimmune disorders, and reagents related thereto
Inventors: William W. Bachovchin and Vijay K. Kuchroo
U.S. patent 8,410,053, issued April 2, 2013, to Tufts University and Brigham & Women's Hospital

Escherichia coli mutants and methods of use thereof
Inventors: Matthew K. Waldor and Theresa D. Ho
U.S. patent 8,414,903, issued April 9, 2013

Self-encoding sensor with microspheres
Inventors: David R. Walt and Todd A. Dickinson
U.S. patent 8,426,217, issued April 23, 2013

Devices and methods for restoring low-resolution text images
Inventors: Joseph P. Noonan and Prabahan Basu
U.S. patent 8,437,551, issued May 7, 2013

Niacin mimetics, and methods of use thereof
Inventors: William W. Bachovchin, Hung-sen Lai, Daniel Philip O'Connell, Wengen Wu and
Christopher P. Kiritsy
U.S. patent 8,450,316, issued May 28, 2013, to Tufts University and Arisaph Pharmaceuticals

Methods and arrays for detecting cells and cellular components in small defined volumes
Inventors: David R. Walt and David M. Rissin
U.S. patent 8,460,878, issued June 11, 2013

Methods and arrays for target analyte detection and determination of target analyte concentration in solution
Inventors: David R. Walt and David M. Rissin
U.S. patent 8,460,879, issued June 11, 2013

Nucleic acids encoding peptides for treating wounds, anti-angiogenic compounds and uses thereof
Inventor: Ira M. Herman      
U.S. patent 8,466,106, issued June 18, 2013

Methods for the delivery of toxins or enzymatically active portions thereof
Inventors: George A. Oyler, Charles B. Shoemaker and Chuehling Kuo
U.S. patent 8,492,109, issued July 23, 2013

7-substituted tetracycline compounds
Inventors: Mark L. Nelson, Roger Frechette, Peter Viski, Mohamed Ismail, Todd Bowser, Beena Bhatia, David Messersmith, Laura McIntyre, Darrell Koza, Glen Rennie, Paul Sheahan, Paul Hawkins, Atul Verma, Tadeusz Warchol and Upul Bandarage
U.S. patent 8,492,365, issued July 23, 2013, to Tufts University and Paratek Pharmaceuticals

pH-induced silk gels and uses thereof
Inventors: David L. Kaplan, Tuna Yucel, Tim Jia-Ching Lo and Gary G. Leisk
U.S. patent 8,501,172, issued August 6, 2013

Fibrous protein fusions and use thereof in the formation of advanced organic/inorganic composite materials
Inventors: David L. Kaplan, Jia Huang, Cheryl Wong Po Foo, Rajesh Naik and Anne George
U.S. patent 8,501,437, issued August 6, 2013, to Tufts University, U.S. Air Force, and University of Illinois

Soft protease inhibitors, and pro-soft forms thereof
Inventors: William W. Bachovchin, Hung-sen Lai and Wengen Wu
U.S. patent 8,513,187, issued August 20, 2013

Method of regulating glucose metabolism, and reagents related thereto
Inventors: William W. Bachovchin, Andrew G. Plaut and Daniel J. Drucker
U.S. patent 8,513,190, issued August 20, 2013, to Tufts University, New England Medical Center Hospitals and 1149336 Ontario

Biopolymer sensor and method of manufacturing the same
Inventors: David L. Kaplan, Fiorenzo Omenetto, Brian Lawrence, Mark Cronin-Golomb and
Irene Georgakoudi
U.S. patent 8,529,835, issued September 10, 2013

Inhibitors of extracellular HSP90
Inventors: Daniel G. Jay, Brenda K. Eustace and Takashi Sakurai
U.S. patent 8,529,891, issued September 10, 2013

Silk-based drug delivery system
Inventors: David L. Kaplan and Lorenz Meinel
U.S. patent 8,530,625, issued September 10, 2013, to Tufts University and Eidgenossisches Technische Hochschule, Zurich