Adaptive Statistical Power Designs

Very often a new research design is confronted with the question of how much data do I need…? Power Analysis software is widely available to address many of the standard fixed sample size solutions to this question and its many variants. Use of these tools can be difficult from the researcher’s point of view in the sense of prior information elicitation needed as input. StatXact software has 3 products, East, Compass and SiZ, that should be considered for dealing with many of these tasks. However, recent work on adaptive power designs has added new options that adjust required fixed sample sizes at interim points of implementation so that desired power is targeted. A paper by Metha and Pocock, Adaptive Increase in Sample Size when Interim Results are Promising, presents the theory and case studies illustrating the advantages of Adaptive Designs.

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