Study of Patent Ductus Arteriosus (PDA) in Pembroke Welsh Corgis

Status:  Fully enrolled

Description: Congenital heart defects occur in a variety of dog breeds, with the most common being the patent ductus arteriosus (PDA).  Although this is a correctable disorder in most puppies, it requires surgery or a catheter-based procedure which can be expensive and is not without risk.  Therefore, determining the genetic cause of PDA in dogs would be highly desirable so that dogs could be screened and the genetic mutation could be eventually bred out of the canine population.  Corgis are a breed at increased risk for PDAs, so the goal of this study is to evaluate Corgis with and without PDAs in order to identify the gene mutation for this heart problem.

Inclusion Criteria:                                      

Pembroke Welsh Corgis with a documented PDA will be studied.

Exclusion Criteria:

Breeds other than Pembroke Welsh Corgis.

Client Benefits:

The study will cover the cost of an echocardiogram (ultrasound of the heart) as well as a blood sample for DNA testing.

Contact Information:

For questions regarding the clinical trial please email the clinical trials technician, Diane Welsh at: