Clinical trials for Cardiology specialty
To determine whether administration of beta-blockers results in either a prolonged survival or a longer time until recurrence of pericardial effusion in dogs with hemangiosarcoma.
Dogs with pericardial effusion and a right atrial mass identified on echocardiogram are eligible for the study.
Dogs with certain severe irregular heart rhythms (e.g., ventricular tachycardia) and dogs who have surgery for the condition.
The results of this study will help us determine whether treatment with beta-blockers improves the outcome in dogs with this disease. The cost of the recheck echocardiogram is covered by the study.
Dr. John Rush
Phone: (508) 839-5395, ext. 8-4696.
We have started a new study to evaluate the use of ultrasound as a quick and non-invasive method of measuring muscle mass in dogs. In many of the common diseases of dogs, such as heart failure, kidney disease, and cancer, a big problem that occurs is muscle loss. This muscle loss is important because it can make dogs weak and can negatively affect their quality of life. We have been studying methods of diagnosing and treating cachexia (the muscle loss that occurs with various diseases) for over 15 years. We are currently evaluating whether ultrasound, an non-invasive test, can be used to quickly and easily diagnose muscle loss in its early stages.
To be eligible, dogs must be healthy 1-5 year old, neutered dogs (male or female) of the following breeds:
*Cavalier King Charles Spaniel
Dogs must be purebred and should have no heart murmur or other medical problems.
Dogs with heart murmurs or any significant medical conditions
If eligible, the dog will get a free examination at Tufts, will have a small blood sample collected (less than ½ teaspoon; to measure red blood cell count, blood sugar, and an estimate of kidney function), an x-ray of the chest to measure bone size, and an ultrasound of the muscles over his or her back (no shaving required).
In addition to getting the free tests (blood test, x-ray, and ultrasound of the back muscles), this information will be beneficial in the future for dogs with heart disease, kidney disease, cancer, and other common diseases by validating an easy ultrasound test to measure muscle mass.
Dr. Lisa Freeman Phone: (508) 887-4696