Neurology

Clinical trials for Neurology specialty

  • Diagnostic Value and Discriminatory Ability of Proton Magnetic Resonance Spectroscopy (MRS) for Intracranial Neoplasia in Dogs

    Description

    To evaluate the utility of MRS in non-invasively differentiating brain tumor types in dogs. MRS is an additional imaging study that can be done in conjunction with the MRI. The study includes any additional fees incurred for anesthesia and imaging for the MRS imaging only. It does not include fees for the MRI or the anesthesia required for the MRI.

    Inclusion Criteria

    Dogs with MRI findings consistent with a brain tumor. The study will include 24 dogs.

    Exclusion Criteria

    Unstable patients who would be at increased risk with a longer anesthesia time are excluded from the study.

    Client Benefits

    Preliminary results have shown differences in gliomas and meningiomas as compared to normal dogs. MRS is also non-invasive, therefore there are no additional risks for the patient.

    Contact Information

    Dr. Katie Weiss, DVM
    Phone: (508) 887-4696

  • Prognostic value of degree of disc material dispersion in nonambulatory dogs with thoracolumbar IVDD
    Description
    The objective of this study is to evaluate whether quantitative MRI assessments after acute thoracolumbar disc extrusion are predictive of long term outcome through measurement of longitudinal dispersion of extruded disc material.
    Inclusion Criteria
    Only chondrodystrophic, nonambulatory paraparetic or paraplegic dogs with or without pain perception (<48 hours), an extradural spinal cord compression at T3 – L3 diagnosed by MRI, a disc extrusion confirmed at the time of the surgery and a detailed follow-up will be included.
    Exclusion Criteria
    Dogs with concurrent disorders incompatible with long-term survival will be excluded.
    Client Benefits
    Two week, 1 month and, if needed, 2 month and 3 month post operative recheck appointments will be paid for by the study.
    Contact Information
    Dr. Tracy Sutton Phone: (508) 887-4696