ACVECC Seminal Articles

This list contains articles 3-­10 years old from core journals and articles within the last  10 years from non-­‐core journals and is designed to bridge a perceived gap in the recommended reading between recent journal articles, non-­‐core journals and textbooks. It contains articles the committee deems likely to inform and impact
the practice of veterinary ECC. We aim to keep this list to <100 articles and will review and update it annually.


1. Drobatz KJ, Cole SG. The influence of crystalloid type on acid-base and electrolyte status of cats with urethral obstruction. J Vet Emerg Crit Care 2008; 18(4):355-361.  article pdf

2. Finfer S, Bellomo R, Boyce N, French J, Myburgh J, Norton R. A comparison of albumin and saline for fluid resuscitation in the intensive care unit. New Engl J Med. 2004; 350(22):2247-2256. article pdf

3. Holowaychuk MK, Hansen BD, DeFrancesco TC, Marks SL. Ionized hypocalcemia in critically ill dogs. J Vet Intern Med 2009; 23(3): 509-513. article pdf

4. Hopper K, Haskins SC. A case-based review of a simplified quantitative approach to acid-base analysis. J Vet Emerg Crit Care 2008; 18(5):467-476. article pdf

5. Martin LG, Luther TY, Alperin DC, et al. Serum antibodies against human albumin in critically ill and healthy dogs. J Am Vet Med Assoc 2008; 232(7):1004-1009. article pdf

6. Perel P, Roberts I. Colloids versus crystalloids for fluid resuscitation in critically ill patients. Cochrane Database Syst Rev. 2012 Jun 13;6:CD000567. article pdf

7. Silverstein DC, Aldrich J, Haskins SC, Drobatz KJ, Cowgill LD. Assessment of changes in blood volume in response to resuscitative fluid administration in dogs. J Vet Emerg Crit Care. 2005; 15(3):185-192. article pdf

8. Valverde A, Hatcher ME, Stampfli HR. Effects of fluid therapy on total protein and its influence on calculated unmeasured anions in the anesthetized dog. J Vet Emerg Crit Care 2008; 18(5):480-487. article pdf


9. Aarnes TK, Bednarski RM, Lerche P, et al. Effect of intravenous administration of lactated Ringer’s solution or hetastarch for the treatment of isoflurane-induced hypotension in dogs. Am J Vet Res 2009; 70(11):1345-1353. article pdf

10. Morton CM, Reid J, Scott EM, Holton LL, Nolan AM. Application of a scaling model to establish and validate an interval level pain scale for assessment of acute pain in dogs. Am J Vet Res. 2005; 66(12):2154-2166. article pdf


11. Biomarkers in Veterinary Cardiology. J Vet Cardiol 2009; 11(S1):S1-S98. link to issue

12. Brady CA, Hughes D, Drobatz KJ. Association of hyponatremia and hyperglycemia with outcome in dogs with congestive heart failure. J Vet Emerg Crit Care. 2004; 14(3):177-182. article pdf

13. Haskins S, Pascoe PJ, llkiw JE, Fudge J, Hopper K, Aldrich J. Reference cardiopulmonary values in normal dogs. Comp Med. 2005; 55(2):156-161. article pdf

14. Haskins SC, Pascoe PJ, llkiw JE, Fudge M, Hopper K, Aldrich J. The effect of moderate hypovolemia on cardiopulmonary function in dogs. J Vet Emerg Crit Care. 2005; 15(2):100-109. article pdf

15. MacDonald KA, Cagney O, Magne ML. Echocardiographic and clinicopathologic characterization of pericardial effusion in dogs: 107 cases (1985-2006). J Am Vet Med Assoc 2009; 235(12): 1456-1461. article pdf

16. Oyama MA, Rush JE, Rozanski EA, et al. Assessment of serum N-terminal pro-B-type natriuretic peptide concentration for differentiation of congestive heart failure from primary respiratory tract disease as the cause of respiratory signs in dogs. J Am Vet Med Assoc 2009; 235(11): 1319-1325. article pdf

17. Stokol T, Brooks M, Rush JE, Rishniw M, Erb H, Rozanski E, Kraus MS, Gelzer AR. Hypercoagulability in cats with cardiomyopathy. J Vet Intern Med 2008; 22(3):546-552. article pdf

18. Tag TL, Day TK. Electrocardiographic assessment of hyperkalemia in dogs and cats. J Vet Emerg Crit Care 2008; 18(l):61-67. article pdf

19. Vincent JL, Rhodes A, Perel A, Martin GS, Rocca GD, Vallet B, Pinsky MR, Hofer CK, Teboul JL, de Boode WP, Scolletta S, Vieillard-Baron A, De Backer D, Walley KR, Maggiorini M, Singer M. Clinical review: Update on hemodynamic monitoring – a consensus of 16. Crit Care. 2011; 15(4):229. article pdf


20. Callan MB, Appleman EH, Sachais BS. Canine platelet transfusions. J Vet Emerg Crit Care 2009; 19(5):401-415. article pdf

21. Estrin MA, Wehausen CE, Jessen CR, Lee JA. Disseminated intravascular coagulation in cats. J Vet Intern Med. 2006; 20(6):1334-1339. article pdf

22. Marik PE, Corwin HL. Acute lung injury following blood transfusion: Expanding the definition. Crit Care Med 2008; 36(ll):3080-3084. article pdf

23. Napolitano LM, Kurek S, Luchette FA, et al. Clinical practice guideline: Red blood cell transfusion in adult trauma and critical care. Crit Care Med 2009; 37(12): 3124-3157. article pdf

24. Pachtinger GE, Otto CM, Syring RS. Incidence of prolonged prothrombin time in dogs following gastrointestinal decontamination for acute anticoagulant rodenticide ingestion. J Vet Emerg Crit Care 2008; 18(3):285-291. article pdf

25. Smith SA. The cell-based model of coagulation. J Vet Emerg Crit Care. 2009; 19(1):3-10. article pdf

26. Wiinberg B, Jensen AL, Johansson PI, Kjelgaard-Hansen M, Rozanski E, Tranholm M, et al. Development of a model based scoring system for diagnosis of canine disseminated intravascular coagulation with independent assessment of sensitivity and specificity. Vet J. 2010; 185(3):292-298. article pdf


27. Zeugswetter F, Handl S, Iben C, Schwendenwein I. Efficacy of plasma beta-hydroxybutyrate concentration as a marker for diabetes mellitus in acutely sick cats. J Feline Med Surg. 2010; 12(4):300-5. article pdf


28. Betten DP, Vohra RB, Cook MD, Matteucci MJ, Clark RF. Antidote use in the critically ill poisoned patient. J Intensive Care Med. 2006; 21(5):255-277. article pdf

29. Connally HE, Thrall MA, Hamar DW. Safety and efficacy of high-dose fomepizole compared with ethanol as therapy for ethylene glycol intoxication in cats. J Vet Emerg Crit Care 2010; 20(2):191-206. article pdf

30. American Academy of Clinical Toxicology Position Statements

31. Jamaty C, Bailey B, Larocque A, Notebaert E, Sanogo K, Chauny JM. Lipid emulsions in the treatment of acute poisoning: a systematic review of human and animal studies. Clin Toxicol. 2010; 48(l):l-27. article pdf


32. Boysen SR, Rozanski EA, Tidwell AS, Holm JL, Shaw SP, Rush JE. Evaluation of a focused assessment with sonography for trauma protocol to detect free abdominal fluid in dogs involved in motor vehicle accidents. J Am Vet Med Assoc. 2004; 225(8):1198-1204. article pdf

33. de Smet AMGA, Kluytmans JAJW, Cooper BS, et al. Decontamination of the digestive tract and oropharynx in ICU patients. New Engl J Med 2009; 360(1): 20-31. article pdf

34. Lisciandro GR, Lagutchik MS, Mann KA, et al. Evaluation of an abdominal fluid scoring system determined using abdominal focused assessment with sonography for trauma in 101 dogs with motor vehicle trauma. J Vet Emerg Crit Care 2009; 19(5): 426-437. article pdf


35. Prins M, Schellens CJ, van Leeuwen MW, Rothuizen J, Teske E. Coagulation disorders in dogs with hepatic disease. Vet J. 2010; 185(2):163-8. article pdf


36. Helmond SE, Polzin DJ, Armstrong PJ, Finke M, Smith SA. Treatment of immune-mediated hemolytic anemia with individually adjusted heparin dosing in dogs. J Vet Intern Med. 2010; 24(3):597-605. article pdf

37. Sorenmo KU, Harwood LP, King LG, Drobatz KJ. Case-control study to evaluate risk factors for the development of sepsis (neutropenia and fever) in dogs receiving chemotherapy. J Am Vet Med Assoc. 2010; 236(6):650-6. article pdf


38. Latenser BA. Critical care of the burn patient: The first 48 hours. Crit Care Med 2009; 37(10): 2819-2826. article pdf



39. Guidelines for the management of severe traumatic brain injury. J Neurotrauma. 2007; 24(S1):S1-106. link to issue

40. Levine JM, Levine GJ, Boozer L, et al. Adverse effects and outcome associated with dexamethasone administration in dogs with acute thoracolumbar intervertebral disk herniation: 161 cases (2000-2006). J Am Vet Med Assoc 2008; 232(3):411-417. article pdf

41. Roberts I, Yates D, Sandercock P, Farrell B, Wasserberg J, Lomas G, et al. Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial. Lancet. 2004; 364(9442):1321-1328. article pdf

42. Zimmermann R, Hulsmeyer VI, Sauter-Louis C, Fischer A. Status epilepticus and epileptic seizures in dogs. J V Intern Med 2009; 23(5): 970-976. article pdf


43. Brunetto MA, Gomes MO, Andre MR et al. Effects of nutritional support on hospital outcome in dogs and cats. J Vet Emerg Crit Care (San Antonio). 2010; 20(2):224-31. article pdf

44. Chan DL, Rozanski EA, Freeman LM. Relationship among plasma amino acids, C-reactive protein, illness severity, and outcome in critically ill dogs. J Vet Intern Med 2009; 23(3): 559-563. article pdf

45. Finfer S, Chittock DR, Su SY, et al. Intensive versus conventional glucose control in critically ill patients. New Engl J Med 2009; 360(13): 1283-1297. article pdf

46. Holahan M, Abood S, Hauptman J, Koenigsknecht C, Brown A. Intermittent and continuous enteral nutrition in critically ill dogs: a prospective randomized trial. J Vet Intern Med. 2010; 24(3):520-6. article pdf

47. Papa K, Psader R, Sterczer A, Pap A, Rinkinen M, Spillmann T. Endoscopically guided nasojejunal tube placement in dogs for short-term postduodenal feeding. J Vet Emerg Crit Care 2009; 19(6): 554-563. article pdf

48. Ray CC, Callahan-Clark J, Beckel NF, Walters PC. The prevalence and significance of hyperglycemia in hospitalized cats. J Vet Emerg Crit Care 2009; 19(4): 347-351. article pdf


49. Bellomo R, Cass A, Cole L, et al. Intensity of continuous renal-replacement therapy in critically ill patients. New Engl J Med 2009; 361(17): 1627-1638. article pdf

50. Diehl SH, Seshadri R. Use of continuous renal replacement therapy for treatment of dogs and cats with acute or acute-on-chronic renal failure: 33 cases (2002-2006). J Vet Emerg Crit Care 2008; 18(4)370-382. article pdf

51. Lee JA, Drobatz KJ. Characterization of the clinical characteristics, electrolytes, acid-base, and renal parameters in male cats with urethral obstruction. J Vet Emerg Crit Care 2003; 13(4):227-233. article pdf

52. Worwag S, Langston CE. Acute intrinsic renal failure in cats: 32 cases (1997-2004). J Am Vet Med Assoc 2008; 232(5):728-732.  article pdf


53. Pretzer SD. Medical management of canine and feline dystocia. Theriogenology. 2008; 70(3):332-336. article pdf

54. Traas AM. Resuscitation of canine and feline neonates. Theriogenology. 2008; 70(3):343-348. article pdf

55. Traas AM. Surgical management of canine and feline dystocia. Theriogenology. 2008; 70(3):337-342. article pdf


56. Harvey S, Harrison DA, Singer M, Ashcroft J, Jones CM, Elbourne D, et al. Assessment of the clinical effectiveness of pulmonary artery catheters in management of patients in intensive care (PAC-Man): a randomised controlled trial. Lancet. 2005; 366(9484):472-477. article pdf

57. Hopper K, Haskins SC, Kass PH, et al. Indications, management, and outcome of long-term positive pressure ventilation in dogs and cats: 148 cases (1990-2001). J Am Vet Med Assoc 2007; 230(l):64-75. article pdf

58. Kelmer E, Scanson LC, Reed A, Love LC. Agreement between values for arterial and end-tidal partial pressures of carbon dioxide in spontaneously breathing, critically ill dogs. J Am Vet Med Assoc 2009; 235(11): 1314-1318. article pdf

59. Kogan DA, Johnson LR, Jandrey KE, Pollard RE. Clinical, clinicopathologic, and radiographic findings in dogs with aspiration pneumonia: 88 cases (2004-2006). J Am Vet Med Assoc 2008; 233(11):1742-1747. article pdf

60. Kogan DA, Johnson LR, Sturges BK, et al. Etiology and clinical outcome in dogs with aspiration pneumonia: 88 cases (2004-2006). J Am Vet Med Assoc 2008; 233(11):1748-1755. article pdf

61. Lee JA, Drobatz KJ, Koch MW, King LG. Indications for and outcome of positive-pressure ventilation in cats: 53 cases (1993-2002). J Am Vet Med Assoc. 2005; 226(6):924-931. article pdf

62. Lisciandro GR, Lagutchik MS, Mann KA, Voges AK, Fosgate GT, Tiller EG, Cabano NR, Bauer LD, Book BP. Evaluation of a thoracic focused assessment with sonography for trauma (TFAST) protocol to detect pneumothorax and concurrent thoracic injury in 145 traumatized dogs. J Vet Emerg Crit Care 2008; 18(3):258-269. article pdf

63. Pang D, Caulkett JHNA, Duke T. Partial pressure of end-tidal C02 sampled via an intranasal catheter as a substitute for partial pressure of arterial C02 in dogs. J Vet Emerg Crit Care. 2007; 17(2):143-148. article pdf

64. Papazian L, Forel JM, Gacouin A et al. Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med. 2010; 363(12):1107-16. article pdf

65. Rice TW, Wheeler AP, Bernard GR, Hayden DL, Schoenfeld DA, Ware LB; for the National Institutes of Health, National Heart, Lung, and Blood Institute ARDS Network. Comparison of the Sp02/FI02 ratio and the Pa02/FI02 ratio in patients with acute lung injury or ARDS. Chest. 2007; 132(2):410-417. article pdf

66. Wheeler AP, Bernard GR, Thompson BT, Schoenfeld D, Wiedemann HP, deBoisblanc B, et al. Pulmonary artery versus central venous catheter to guide treatment of acute lung injury. New Engl J Med. 2006; 354(21):2213-2224. article pdf

67. Wiedemann HP, Wheeler AP, Bernard GR, Thompson BT, Hayden D, deBoisblanc B, et al. Comparison of two fluid-management strategies in acute lung injury. New Engl J Med. 2006; 354(24):2564-2575. article pdf

68. Wilkins PA, Otto CM, Baumgardner JE, Dunkel B, Bedenice D et al. Acute lung injury and acute respiratory distress syndromes in veterinary medicine: consensus definitions: The Dorothy Russell Havemeyer Working Group on ALI and ARDS in Veterinary Medicine. J Vet Emerg Crit Care. 2007; 17(4):333-339. article pdf


69. Annane D, Vignon P, Renault A, Bollaert PE, Charpentier C, Martin C, et al. Norepinephrine plus dobutamine versus epinephrine alone for management of septic shock: a randomised trial. Lancet. 2007; 370(9588):676-684. article pdf

70. Black DM, Rankin SC, King LG. Antimicrobial therapy and aerobic bacteriologic culture patterns in canine intensive care unit patients: 74 dogs (January-June 2006). J Vet Emerg Crit Care 2009; 19(5): 489-495. article pdf

71. Burkitt JM, Haskins SC, Nelson RW, Kass PH. Relative adrenal insufficiency in dogs with sepsis. J Vet Int Med. 2007; 21(2):226-231. article pdf

72. Butler AL, Campbell VL. Assessment of oxygen transport and utilization in dogs with naturally occurring sepsis. J Am Vet Med Assoc. 2010; 237(2):167-73. article pdf

73. de Laforcade AM, Rozanski EA, Freeman LM, Li W. Serial evaluation of protein C and antithrombin in dogs with sepsis. J Vet Intern Med 2008; 22(l):26-30. article pdf

74. Duffy AL, Butler AL, Radecki SV, Campbell VL. Comparison of continuous arterial pressure waveform analysis with the lithium dilution technique to monitor cardiac output in conscious dogs with systemic inflammatory response syndrome. Am J Vet Res 2009; 70(11): 1365-1373. article pdf

75. Hayes G, Mathews K, Doig G et al. The acute patient physiologic and laboratory evaluation (APPLE) score: a severity of illness stratification system for hospitalized dogs. J Vet Intern Med. 2010; 24(5):1034-47. article pdf

76. Kellett-Gregory LM, Mittleman Boiler E, Brown DC, Silverstein DC. Ionized calcium concentrations in cats with septic peritonitis: 55 cases (1990-2008). J Vet Emerg Crit Care. 2010; 20(4):398-405. article pdf

77. Kenney EM, Rozanski EA, Rush JE, et al. Association between outcome and organ system dysfunction in dogs with sepsis: 114 cases (2003-2007). J Am Vet Med Assoc. 2010; 236(l):83-7. article pdf

78. Kumar A, Roberts D, Wood KE, Light B, Parrillo JE, Sharma S, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med. 2006; 34(6):1589-1596. article pdf

79. Levy MM, Dellinger RP, Townsend SR, et al. The surviving sepsis campaign: results of an international guideline-based performance improvement programme targeting severe sepsis. Crit Care Med 2010; 38:367-374. article pdf

80. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med. 2003; 31(4):1250-1256. article pdf

81. Luschini MA, Fletcher DJ, Schoeffler GL. Incidence of ionized hypocalcemia in septic dogs and its association with morbidity and mortality: 58 cases (2006-2007). J Vet Emerg Crit Care. 2010; 20(4):406-12. article pdf

82. Marik PE, Pastores SM, Annane D, et al. Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: Consensus statements from an international task force by the American College of Critical Care Medicine. Crit Care Med 2008; 36(6):1937-1949. article pdf

83. Marshall JC, Reinhart K, Forum IS. Biomarkers of sepsis. Crit Care Med 2009; 37(7): 2290-2298. article pdf

84. Ogeer-Gyles JS, Mathews KA, Boerlin P. Nosocomial infections and antimicrobial resistance in critical care medicine. J Vet Emerg Crit Care 2006; 16(1):1-18. article pdf

85. Roberts JA, Lipman J. Pharmacokinetic issues for antibiotics in the critically ill patient. Crit Care Med 2009; 37(3): 840-851. article pdf

86. Rubulotta F, Marshall JC, Ramsay G, Nelson D, Levy M, Williams M. Predisposition, insult/infection, response, and organ dysfunction: A new model for staging severe sepsis. Crit Care Med 2009; 37(4):1329-1335. article pdf

87. Russell JA, Walley KR, Gordon AC, et al. Interaction of vasopressin infusion, corticosteroid treatment, and mortality of septic shock. Crit Care Med 2009; 37(3): 811-818. article pdf

88. Russell JA, Walley KR, Singer J, Gordon AC, Hebert PC, Cooper DJ, et al. Vasopressin versus norepinephrine infusion in patients with septic shock. New Engl J Med. 2008; 358(9):877-887. article pdf

89. Sprung CL, Annane D, Keh D, Moreno R, Singer M, Freivogel K, et al. Hydrocortisone therapy for patients with septic shock. New Engl J Med. 2008; 358(2):111-124. article pdf


90. American Heart Association. 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2010; 122(S3):S640-933. link to issue

91. Antonelli M, Levy M, Andrews PJ, Chastre J, Hudson LD, Manthous C, Meduri GU, Moreno RP, Putensen C, Stewart T, Torres A. Hemodynamic monitoring in shock and implications for management. International Consensus Conference, Paris, France, 27-28 April 2006. Intensive Care Med. 2007; 33(4):575-590. article pdf

92. CRASH-2 trial collaborators. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 2010; 376(9734):23-32. article pdf

93. De Backer D, Biston P, Devriendt J et al. Comparison of dopamine and  norepinephrine in the treatment of shock. N Engl J Med. 2010; 362(9):779-89. article pdf

94. Hofmeister EH, Brainard BM, Egger CM, Kang S. Prognostic indicators for dogs and cats with cardiopulmonary arrest treated by cardiopulmonary cerebral resuscitation at a university teaching hospital. J Am Vet Med Assoc 2009; 235(1): 50-57. article pdf

95. Silverstein DC, Wininger FA, Shofer FS, King LG. Relationship between Doppler blood pressure and survival or response to treatment in critically ill cats: 83 cases (2003-2004). J Am Vet Med Assoc 2008; 232(6):893-897. article pdf

96. Simpson SA, Syring R, Otto CM. Severe blunt trauma in dogs: 235 cases (1997-2003). J Vet Emerg Crit Care 2009; 19(6): 588-602. article pdf

97. Streeter EM, Rozanski EA, de Laforcade-Buress A, et al. Evaluation of vehicular trauma in dogs: 239 cases (January-December 2001). J Am Vet Med Assoc 2009; 235(4): 405-408. article pdf

98. Zacher LA, Berg J, Shaw SP, Kudej RK. Association between outcome and changes in plasma lactate concentration during presurgical treatment in dogs with gastric dilatation-volvulus: 64 cases (2002-2008). J Am Vet Med Assoc. 2010; 236(8):892-7. article pdf

This list is based on the 2014 reading list. This page was last updated May 2014.