1. Food allergy facts and statistics for the US. Food Allergy Research and Education. Published 2017. Accessed: October 9, 2017.
2. Branum AM, Lukacs SL. Food Allergy Among U.S. Children: Trends in Prevalence and Hospitalizations. NCHS Data Brief . 2008;(10):4.
3. Peanut Institute, The. Peanut Allergy White Paper. Published 2013. Accessed Oct 9, 2017.
4. Di Stasio, L.; Picariello, G.; Mongiello, M.; et al. Peanut digestome: Identification of digestion resistant IgE binding peptides. Food and Chemical Toxicology. 2017, 107a, 88-98.
Link to Article. Link to PubMed.
5. Janeway, C.A.; Travers, P.; Walport, M.; et al. Immunobiology: The Immune System in Health and Disease, 5th ed.; Garland Science: New York, 2001.
6. Mueller, G. A.; Gosavi, R. A.; Pomes, A.; et al. Ara h 2: crystal structure and IgE binding distinguish two subpopulations of peanut allergic patients by epitope diversity. Allergy. 2011, 66(7), 878-885.
Link to Article. Link to PubMed.
7. Mueller GA, Gosavi RA, Moon AF, et al. MBP-fusion protein of the major peanut allergen Ara h 2. RCSB PDB. 2011.
8. Prolamin protein. Britannica.com. Accessed October 9, 2017.
9. Thermo Fisher Scientific. Introduction to Immunoglobulins. Accessed Oct 9, 2017.
10. Dhaliwal B, Sutton BJ, Beavil AJ. The high resolution crystal structure of IgE Fc. RCSB PDB. 2010.
11. Pacific Immunology. What is an Epitope? Accessed Oct 9, 2017.
12. World Allergy Organization IgE in Clinical Allergy and Allergy Diagnosis. Published May, 2003. Updated July, 2015. Accessed Oct 9, 2017. WAS 16
13. Jones, S. M.; Pons, L.; Roberts, J. L.; et al. Clinical Efficacy and Immune Regulation With Peanut Oral Immunotherapy. The Journal of Allergy and Clinical Immunology. 2009, 124(2), 292-30197.
Link to Article. Link to PubMed.
14. Vickery, B.P.; Lin, J.; Kulis, M.; et al. Peanut oral immunotherapy modifies IgE and IgG4 responses to major peanut allergens. The Journal of Allergy and Clinical Immunology. 2013;131(1):128-134.e3.
Link to Article. Link to PubMed.
15. Beyer K, Ellman-Grunther L, Järvinen K-M, Wood RA, Hourihane J, Sampson HA. Measurement of peptide-specific IgE as an additional tool in identifying patients with clinical reactivity to peanuts. Journal of Allergy and Clinical Immunology. 2003;112(1):202-207.
Link to Article. Link to PubMed.
16. Stone KD, Prussin C, Metcalfe DD. IgE, Mast Cells, Basophils, and Eosinophils. The Journal of allergy and clinical immunology. 2010;125(2 Suppl 2):S73-S80.
Link to Article. Link to PubMed.
17. Spahn J, Covar R, Stempel DA. Asthma: addressing consistency in results from basic science, clinical trials, and observational experience. Journal of Allergy and Clinical Immunology. 2002; 109(5):490-502
18. Nunomura, S.; Gon, Y.; Yoshimaru, T.; et al. Role of the FcƐRI β-chain ITAM as a signal regulator for mast cell activation with monomeric IgE. International Immunology. 2005, 17(6), 685-694.
19. Isakov, N. Immunoreceptor tyrosine-based activation motif (ITAM), a unique module linking antigen and Fc receptors to their signaling cascades. Journal of Leukocyte Biology. 1997, 61(1), 6-16.
Link to Article. Link to PubMed.
20. Gilfillan, A. M., Tkaczyk, C. Integrated signalling pathways for mast-cell activation. Nature Reviews Immunology. 2006, 6, 218-230.
21. Gross, P., Jean-Baptiste, F., Lemba, T. A. S., Zoror, K. Signalling by ghrelin, insulin, and leptin in the hypothalamus. Cell Biology Promotion. Accessed December 5, 2017.
22. Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002.
23. Santos AF, James LK, Bahnson HT, et al. IgG4 inhibits peanut-induced basophil and mast cell activation in peanut-tolerant children sensitized to peanut major allergens. The Journal of Allergy and Clinical Immunology. 2015;135(5):1249-1256.
Link to Article. Link to PubMed.
24. Strait RT, Morris SC, Finkelman FD. IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and FcyRIIb cross-linking. The Journal of Clinical Investigation. 2006;116(3): 833-841.
Link to Article. Link to PubMed.
25. Stanley, J. S.; King, N.; Burks, A. W.; et al. Identification and Mutational Analysis of the Immunodominant IgE Binding Epitopes of the Major Peanut Allergen Ara h 2. Archives of Biochemistry and Biophysics. 1997, 342(2), 244-253.
Link to Article. Link to PubMed.
26. Johnston LK, Chien KB, Bryce PJ. The Immunology of Food Allergy. Journal of immunology (Baltimore, Md : 1950). 2014;192(6):2529-2534.
Link to Article. Link to PubMed.
27. Food Allergy Research and Education. Peanut Allergies. Accessed October 9, 2017.
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