Clara Cells in Bronchiole Wall

The epithelium in this portion of the bronchiole contains many Clara cells. They are cuboidal cells with round nuclei and pale/white cytoplasm. The Clara cells have the ultrastructure of secretory cells. The secretion contributes to the bronchiolar fluid which may help to reduce surface tension as well. Clara cells are also involved in tissue repair and regeneration. This is an autopsy specimen and it is not clear if the depression represents an opening into an alveolus or is an artifact. PK1588. S1. Original mag. 100 x. H&E. Clara cells. Bronchiole. Lung. Respiratory System.