MR spectroscopy: Magnetic resonance spectroscopy (MRS), also known as nuclear magnetic resonance (NMR) spectroscopy, is a non-invasive analytical technique that has been used to study metabolic changes in brain tumors, strokes and other diseases affecting the brain. Dr. March is currently leading a clinical trial to evaluate the use of the technique for the definitive diagnosis of primary brain tumors and strokes.

Stem cell therapy for immune-mediated meningoencephalitis: Dr. March is conducting a trial designed to determine whether after initial stabilization with current treatment approaches, stem cell therapy allows dogs to remain in clinical remission.

Intervertebral disk disease: Dr. Faissler recently completed a clinical trial evaluating the use of trophic factors such as platelet rich plasma and erythropoietin for stimulating spinal cord repair in paraplegic dogs with loss of pain perception in both hind legs – analysis of the results is pending.  We are planning and continuing to explore  novel treatment options for dogs with severe spinal cord damage, including stem cell transplantation. Under the supervision of Dr. Faissler, Dr. Sutton is investigating prognostic factors for paralyzed dogs with intervertebral disk herniation. Our hypothesis is that the degree of dispersion of extruded disk material correlates with outcome.

Brain surgery:  Dr. Faissler has introduced intracranial pressure (ICP) during and, most importantly, after brain surgery.  Knowledge of ICP has improved patient outcomes. Dr. Faissler has also developed a technique for closing large skull defects resulting from cranioectomies which uses a combination of titanium and bone cement. Because titanium is non-ferromagnetic, MRI for assessment of tumor control can be performed during the postoperative period.