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EntoCellular: Redefining Sustainable Pet Nutrition

EntoCellular is taking significant strides in its mission to provide sustainable and ethical protein for the pet food industry. Co-founders Sophie Letcher and Michael Saad, both recent PhD graduates from the Kaplan Lab, are leveraging over a decade of research into insect cell culture to create “entoprotein.” This real animal protein is produced without the environmental or ethical drawbacks of traditional factory farming. In recent talks at the Tufts Cellular Agriculture Innovation Day and IdeaCon, Sophie shared her entrepreneurial journey and highlighted how insect cells offer a more resilient and cost-effective pathway to scaling cultivated meat. The team has already… Read More »EntoCellular: Redefining Sustainable Pet Nutrition

Shifting Gears: David Kaplan on the Future of Cellular Agriculture

At the 2026 Tufts Future Food Innovation Day, David Kaplan joined Bruce Friedrich to discuss how cellular agriculture is moving beyond the initial startup phase and into a more mature era of public-sector and institutional support. David shared his insights on the “second wave” of specialized companies entering the field and emphasized the need for better communication regarding the safety, control, and food security benefits of cultivated products. See below for a full playlist of all of the talks during the 2026 Tufts Future Food Innovation Day: Citation: Cellular ag moves beyond the startup phase

Dr. Camilo Riquelme-Guzmán Receives the “Dr. Humberto Maturana Romesín” Prize

The Kaplan Lab is incredibly proud to celebrate postdoctoral researcher Dr. Camilo Riquelme-Guzmán for receiving the prestigious “Dr. Humberto Maturana Romesín” prize for early career researchers. Awarded by the Chilean Society for Biology at their annual meeting in Valparaíso, this honor recognizes Camilo’s outstanding contributions to biological research. During the event, Camilo joined fellow awardees Diyanira Castillo Novales, Simón P. Castillo, and Korina Ocampo-Zuleta to present their work and discuss the future of the field with distinguished leaders like Dr. Michael Seeger and Dr. Rosa Devés. Camilo expressed deep gratitude for the mentors and colleagues who have supported his scientific… Read More »Dr. Camilo Riquelme-Guzmán Receives the “Dr. Humberto Maturana Romesín” Prize

Natalie Rubio on the Journey of Cellular Agriculture

In this TEDxTufts talk, Dr. Natalie Rubio, a former PhD student in the Kaplan Lab, shares her decade long passion for cellular agriculture and the quest to produce meat from cells rather than animals. She recounts her unique research into growing meat from insect cells, which led to a NASA grant to study “space food,” and discusses the evolution of the field from theoretical idealism to the practical realities of industrial scaling. Dr. Rubio highlights the current challenges facing the industry, including high production costs and the technical difficulty of creating structured products like steaks. Despite these hurdles, she remains… Read More »Natalie Rubio on the Journey of Cellular Agriculture

2025 Fireside Chat: Insights from David Kaplan and Bruce Friedrich

At the 2025 Tufts University Cellular Agriculture Innovation Day, David Kaplan and Bruce Friedrich, president of the Good Food Institute, discuss the evolving state of cellular agriculture. They reflect on a year of significant progress, highlighted by major funding initiatives like the Bezos Earth Fund and deepening government support globally. Professor Kaplan emphasizes the importance of a collaborative scientific ecosystem and mentions the upcoming first Gordon Research Conference dedicated to future foods in 2026. The conversation addresses critical challenges such as the need for innovative scale up solutions beyond traditional pharmaceutical methods. David Kaplan calls for new paradigms in bioreactor… Read More »2025 Fireside Chat: Insights from David Kaplan and Bruce Friedrich

Cultivated Meats: Pioneering Safety in Next-Gen Proteins

In a presentation at the ILSI AM2024, David Kaplan introduces the core concepts and future of cellular agriculture, focusing on the production of meat and dairy products directly from animal cells. He outlines the basic paradigm of isolating cells, multiplying them in bioreactors, and using edible scaffolding to create familiar food products without the need for traditional animal husbandry. Professor Kaplan also discusses the significant challenges facing the industry, such as scaling manufacturing, reducing costs, and ensuring safety, while highlighting the unique opportunities for “therapeutic foods” engineered for specific nutritional needs.

The State of Cellular Agriculture: A Fireside Chat with David Kaplan and Bruce Friedrich

At the Tufts University Cellular Agriculture Innovation Day 2024, David Kaplan and Bruce Friedrich, president of the Good Food Institute, discuss the current state and future of the cellular agriculture field. Professor Kaplan expresses his “eternal optimism” regarding the industry’s growth, citing the incredible passion and dedication of students who are driving innovation from the ground up. He emphasizes that while the field faces economic and scaling challenges, the continued advancement of core sciences (such as cell isolation and low-cost media development) provides a clear path toward a more sustainable and secure food system.

InSciDE Conference Presentation: American Association of Extracellular Vesicles 2023

Members of the lab including Peter Hsi and Vishal Tandon presented at the American Association of Extracellular Vesicles (AAEV) conference (Boston, MA) in 2023! Their poster presentation was titled “Insights into TBI progression using a 3D brain tissue model to study extracellular vesicles”. Check out more about the conference here: https://www.aaev.org/events-1.

InSciDE Conference Presentation: Advances in 3D Bioprinting and Cerebral Vascular Conferences 2023

Members of the lab including Liam Power, Philip Houtz, Ying Chen, and Michael Whalen presented at both the Advances in 3D Bioprinting Conference (Haifa, Israel) and the Cerebral Vascular Conference (Uppsala, Sweden)! Their poster presentations were titled “Interrogating Mechanisms of Chronic Blood Brain Barrier Damage using 3D In-Vitro Scaffolds”. Check out more about the conferences here: https://bioprinting.net.technion.ac.il/ and https://www.cvb2023.com/.

Draper Scholar Peter Hsi Presents Research on Traumatic Brain Injury

Kaplan Lab PhD student and Draper Scholar, Peter Hsi, recently presented his research on traumatic brain injuries (TBIs) at the 2023 Draper Research Symposium. As part of the Kaplan Lab’s Neuro group, Peter’s work focuses on utilizing a 3D silk model of the brain to investigate biomarkers for diagnosing TBIs and to evaluate potential treatments. This innovative approach, combining the Kaplan Lab’s biomaterial expertise with Draper’s cutting-edge technology, aims to improve our understanding and management of these complex injuries. To learn more, check out the article below! Citation: Draper Scholars present research on injury management (Tufts Now)

InSciDE Conference Presentation: TERMIS Americas 2023

Members of the lab including Marly Coe, Sydni Rosenfeld, Volha Liaudanskaya, Liam Power, Philip Houtz, Ying Chen, and Michael Whalen presented at the TERMIS Americas Annual Conference (Boston, MA) in 2023! Their oral and poster presentations were titled “A 3D Human Brain-like Tissue Model Of Neuro-regeneration After Traumatic Brain Injury” and “3D In-Vitro Scaffold Model of Blood-Brain Barrier” respectively. Check out more about the conference here: https://am2023.termis.org/.

Key Insights from the Inaugural Tufts Cellular Agriculture Innovation Day Keynote

At the inaugural Tufts University Cellular Agriculture Innovation Day, David Kaplan moderates a panel featuring industry pioneers Mark Post, Isha Datar, Bruce Friedrich, and Uma Valeti. The discussion marks a decade of progress since the world’s first cultivated beef burger and evaluates the field’s transition from proving scientific viability to tackling industrial scale up. Panelists emphasize that while cellular agriculture has grown to include over 150 companies globally, the next phase requires significant government investment and shared infrastructure to achieve cost parity with traditional meat production. The speakers highlight the essential role of public and private partnerships in raising this… Read More »Key Insights from the Inaugural Tufts Cellular Agriculture Innovation Day Keynote

73 Questions with David Kaplan: Science, Students, and Cellular Agriculture

In this stylized interview, David Kaplan provides a personal look into the daily life and inspirations behind the Kaplan Lab. He shares the history of the Biomedical Engineering department at Tufts, which he helped found over twenty years ago to meet a surge in student interest. Throughout the conversation, Professor Kaplan emphasizes that his primary motivation is his students, highlighting the passion and leadership of early researchers like Natalie Rubio, who helped establish the cellular agriculture program in earnest seven years ago. The discussion also covers the lab’s significant milestones, including a major USDA grant that has allowed Tufts to… Read More »73 Questions with David Kaplan: Science, Students, and Cellular Agriculture

The Future of Food: Scaling Alternative Proteins

In this SXSW panel, experts discuss the rapidly evolving landscape of alternative proteins, focusing on the technological and financial milestones needed to bring cultivated meat to the mainstream. Dr. Natalie Rubio, representing Arc Biotech and the Kaplan Lab, shares her insights on the transition from academic research to the private sector and the critical need for specialized bioreactors. The conversation highlights the collaborative spirit between startups, non-profits like the Good Food Institute, and government bodies to overcome hurdles such as high production costs and regulatory approvals. The panelists remain optimistic about the potential for these technologies to address global challenges… Read More »The Future of Food: Scaling Alternative Proteins

Entomoculture: Reimagining the Future of Food with Insect Cells

In this presentation from the New Harvest 2019 Conference, Natalie Rubio introduces the concept of entomoculture, which combines the sustainability of edible insects with the technology of cellular agriculture. She argues that culturing insect cells offers significant advantages over traditional mammalian cell culture, as insect cells are more robust and can grow at room temperature in simpler, serum free media. By targeting specific muscle and fat body tissues, this research aims to create familiar, high protein food products that avoid the sensory barriers often associated with eating whole insects. Natalie shares her success in cultivating fruit fly and caterpillar muscle… Read More »Entomoculture: Reimagining the Future of Food with Insect Cells

Exploring the Future of Food with Insect-Based Proteins

In a featured segment from CBS Boston, Natalie Rubio discusses her groundbreaking research at the Kaplan Lab on the potential of insect based cellular agriculture. As a doctoral candidate, she explores using stem cells from tobacco hornworm caterpillars to create sustainable meat and seafood substitutes. This work is driven by a commitment to improving animal welfare and reducing the environmental footprint of our food system, particularly by decreasing the methane emissions and water usage associated with traditional livestock. The research highlights a growing movement toward using advanced biotechnology to solve global food challenges. By growing tissues in a controlled lab… Read More »Exploring the Future of Food with Insect-Based Proteins

Scaffolds 101: Building the Foundation for Cultured Meat

In this 2017 New Harvest presentation, Natalie Rubio discusses the critical role of scaffolding in transforming two dimensional cell cultures into structured meat products like steak or chicken breast. She explains that scaffolds provide the necessary surface area for muscle cells to adhere to and guide their development into organized tissues. While cellular agriculture has historically adapted techniques from the medical industry, Natalie emphasizes that food production introduces unique requirements, as scaffolds must be edible, sustainable, and capable of enhancing the final product’s texture and nutritional profile. Natalie details several potential scaffolding materials, including silk, collagen, and plant derived cellulose.… Read More »Scaffolds 101: Building the Foundation for Cultured Meat

Exploring the Limitless Potential of Silk in High-Tech and Medicine

In this presentation, David Kaplan and Fiorenzo Omenetto discuss their transformative research into “reverse engineering” silk into a versatile, water-based solution that serves as a foundation for a wide array of sustainable technologies. From biocompatible medical implants and non-invasive drug delivery systems to programmable green electronics and shelf-stable vaccine storage, their work showcases how this ancient protein can be reimagined to solve modern challenges in global health and environmental sustainability. Their collaborative efforts continue to push the boundaries of materials science, bridging the gap between nature’s strongest natural polymer and the next generation of high-tech applications.