The Dynamics of Wound Healing

Recent work reveals that wound healing dynamics are tightly and reciprocally regulated. In particular, cellular components within the epidermal and dermal wound microenvironments transduce signals that control extracellular matrix remodeling and wound healing dynamics. In turn, these cellular and extracellular signaling cascades control whether or to what extent wound repair progresses or is chronically impaired. In this recent report, we consider these key aspects of dynamic reciprocity.

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