The Yi-Pin Lin Laboratory is located at The Cummings School for Veterinary Medicine at Tufts University, part of the Department of Infectious Disease and Global Health.

Our laboratory investigates the mechanisms of pathogen-host interactions, in particular how Borrelia burgdorferi, the agent of Lyme disease, and other tick-borne pathogens survive in distinct host environments (ticks and vertebrate hosts), resulting in pathogen transmission between hosts, dissemination, and disease manifestations. We utilize multiple genetic, biochemical, microbiological, and vector biological approaches to define the transmission of Lyme disease bacteria, and other pathogens transmitted by ticks, in the infection cycle.

Information from our studies will facilitate the development of prophylactic and therapeutic strategies to eventually block the route of human infection from Lyme bacteria and other tick-borne pathogens.