WELCOME

The research at the integrated Biofunctional Imaging and Therapeutics Laboratory (iBIT Lab) focuses on utilizing non-invasive acoustic and optical imaging techniques with nanomaterials and biological models to understand the structural, functional, molecular and biomechanical heterogeneity of pathologies such as cancer. The triangle in the iBIT lab logo depicts the three directions where biofunctional imaging will be utilized to improve patient care: 1. Guide surgical methods 2. Predict therapeutic response and 3. Design effective therapeutic strategies. We are a team of Biomedical engineers with interdisciplinary background in Electronics, signal processing, molecular biology, optics and nanotechnology with collaborations with clinicians and researchers in the  Boston Area. We are always looking for enthusiastic highly motivated individuals to join our team.

We are actively looking for graduate students to join our Group. Students interested in non-invasive ultrasound and optical imaging with focus on image-guided therapies and cancer research, email Prof. Mallidi your CV. We also have openings for Postdoctoral fellows. Check out the current openings here.


02/23/2024

EP just dropped

01/23/2024

Marvin defends his PhD dissertation!

11/06/2023

Andrew teaches about Photoacoustic Imaging and Brooke teaches about Nanoparticle Synthesis at the Reverse Science Fair at Medford High School

05/20/2023

Congratulations to the iBITers class of 2023!

04/28/2023

Andrew Wins De Florez Prize in Human Engineering and Howard Sample Prize in Physics!

04/28/2023

Valli Wins Engineering Faculty Mentorship Award

02/16/2023

Look at who’s on the internet – Patrick and Andrew

Check it out here

02/01/2023

iBIT takes SPIE Photonics West

Our lab visited San Fransisco to attend the SPIE Photonics West 2023 Conference! Chris, Skye, and Avijit gave great talks along with Marvin and Deeksha’s poster presentations! It was amazing to meet researchers from all over the world working on the development of Photoacoustic Imaging and Photodynamic Therapy.

12/14/2022

Holiday Celebration

The iBIT Team played Yankee Swap to celebrate the end of the year!

11/30/2022

SPIE Travel Awards

Congratulations to Avijit, Chris, and Deeksha who all received travel awards to present their research at the 2023 SPIE Photonics West Congress in San Fransisco.

11/18/2022

BME Research Retreat

Loved having the opportunity to share the research we do with the rest of the Tufts BME department

11/14/2022

Lab Potluck!

the jury is still out on who made the best biriyani

09/09/2022

Optics Club Social

iBITers welcoming new graduate students at the Optics Club Social!

08/24/2022

Visit to Northeastern University!

Amazing gathering and scientific discussions happened today when the Optics groups of Tufts visited Northeastern

 

08/11/2022

TUBERS visit the lab!

Tufts University Biomedical Engineering Research Scholars ​(TUBERS) Program is for dedicated, academically-talented high school students. Some Tubers came to visit the lab and learn more about our research this summer!

08/05/2022

RO1 Grant Awarded!

Excited to share the news that we received R01 grant from the NIH National Cancer Institute to work on photoacoustic image-guided photodynamic therapy with nanodroplets to improve outcomes in head and neck cancer in collaboration with Nanohybrids Inc!

08/05/2022

End of Summer 2022 Lab Party

08/01/2022

Allison Passes Master’s Thesis Defense!

07/14/2022

Photoacoustic Monitoring of Suboptimal Therapy Efficacy

Just published from the iBIT Lab in the Frontiers in Oncology Cancer Imaging and Image-directed Interventions special issue. Read here

07/03/2022

Dr. Mallidi’s 40th Birthday

Happy Birthday Dr. Mallidi!

06/10/2022

UG students take over lab meeting!

06/08/2022

Skye, Deeksha, and Avijit Pass PhD Qualifiers!

06/01/2022

Marvin passes his ORP!

05/24/2022

NESS Translational Research Award

Congratulations to our very own Allison Sweeney for winning the New England Science Symposium’s Prophet Genomics Translational Research Award!

05/22/2022

Publication on Biodegradable Nanoparticles for PDT

Publication hot off the press from iBIT lab – Biodegradable Eutectic Gallium–Indium Nanoparticles fabricated via simple green sonication methods can be used for delivery of photosensitizers to the tumor for localized Photodynamic Therapy. Read here

05/20/2022

Congratulations to our Master’s Graduates

Congratulations to our Graduates! Special mention to Abigail Claus and Allison Sweeney, the first set of Master’s students to graduate from iBIT Lab! Abby is heading to Invicro and Allison decided to stay with us longer to research further on photoacoustics

05/15/2022

Allison Wins 2022 Pride on the Hill Award!

The award honors undergraduate or graduate students who, through community involvement, artistic expression, written work, or scientific research have contributed the most to an understanding at Tufts of gay, lesbian, bisexual, or trans identities during the preceding academic year.

05/13/2022

Grad Student Team

look at them go!

05/13/2022

Dr. Mallidi wins BEaChES Exemplary Engineer Award

The BME faculty recipient of this year’s award is Professor Srivalleesha Mallidi!

05/12/2022

BME Capstone Project Win

BME Capstone Best senior design project of the Year! Congratulations to these amazing young researchers in the Oudin Lab, and our very own Elli Diaz!

04/21/2022

Abby Passes Master’s Thesis Defense

04/20/2022

Skye and Allison awarded at Tufts Graduate Student Research Symposium

04/13/2022

Mallidi named rising star

Dr. Mallidi has received a Rising Star Award from the World Molecular Imaging Congress. The award recognizes the contributions of outstanding women scientists in their early careers who demonstrate exceptional potential for contributions to the field of molecular imaging.

04/08/2022

Dr. Mallidi Speaks at Columbia

Dr. Mallidi presents on ultrasound guided photoacoustic imaging for treatment at Columbia’s BME Seminar Series. Watch here!

03/01/2022

R21 Grant Awarded

The iBIT Lab along with the Shelly Foster Group at UMASS Boston are the proud recipients of an R21 Grant!

03/01/2022

Chris passes his ORP!

02/02/2022

Vevo LAZR-X in Action!

11/20/2021

Lab Swag 🙂

09/06/2021

Jenny in action!

The histology queen is working hard

09/02/2021

Light on Tissue!

Light on Tissue cool stuff happening in lab!

08/20/2021

Allison and Abby pass Master’s ORP

Congrats to the iBIT Lab’s first Master’s students!

08/06/2021

2021 Tubers Summer Program

Local high school students come to tour the lab and learn about the science we do!

09/05/2020

Publication on Frontiers in Placenta Imaging

Checkout our review paper here, headed by Chris Nguyen, on placenta imaging with Dr. Mary Wallingford group! We are excited about this collaboration and new directions for photoacoustic and photodynamic therapy!

 

08/14/2020

Study on LED-Photoacoustic Imaging for imaging tumor vasculature is now published

Access paper here. Traditionally photoacoustic systems employ expensive and bulky class IV lasers with low pulse repetition rate, due to which its availability for preclinical cancer research is hampered. In this study, we evaluated the capability of a Light-Emitting Diode (LED)-based PA and ultrasound (US) imaging system for monitoring heterogeneous microvasculature in tumors (up to 10 mm in depth) and quantitatively compared the PA images with gold standard histology images.  Analysis of 30 regions of interest in tumors from different mice showed a statistically significant R-value of 0.84 where the areas with high blood vessel density had high PA response while low blood vessel density regions had low PA response. Our results confirm that LED-based PA and US imaging can provide 2D and 3D images of tumor vasculature and the potential it has as a valuable tool for preclinical cancer research.

 

07/16/2020

Imaging equipment is here!

The Vevo LAZR-X ultrasound and photoacoustic imaging system is here! We recently received NIH funds to purchase this equipment. We cannot wait for the labs to fully reopen to hook this system up and look inside of tumors!

07/07/2020

New iBIT Lab publication

Does angle of illumination really matter in LED based photoacoustic imaging for deep tumor imaging? Check out our new publication here in Sensors that answers this question with 3D printed flexible angle holder!

06/14/2020

NIH S10 Award for Dr. Mallidi

Dr. Mallidi has received an S10 award to  setup a small animal imaging core at the Medford Campus! The first instrument in the core is FujiFILM VisualSonics Ultrasound and photoacoustic imaging instrument

06/05/2020

Chris & Marvin pass Qualifiers

iBIT Labs first batch of graduate students- Chris Nguyen and Marvin Xavierselvan pass the PhD qualifiers! Congratulations!

 

05/22/2020

Paper published in JSR

Our work with Redmond team at MGH is now published in JSR. We showcase the utility of high frequency ultrasound  imaging in cardiovascular research – particularly to measure intima/media thickness and blood flow in diseased and treated Pig vessels in vivo. Read the paper here

05/06/2020

We are on Tufts NEWS!

Read more about it here

04/21/2020

UG Kelsey Detels wins the Audrey Butvavy Gruss Science Award

Congratulations Kelsey!She won the Audrey Butvavy Gruss Science Award for Juniors/seniors  for the year 2020. Awarded annually to a student who has demonstrated outstanding academic work in any of the sciences and who is a scholarship recipient. This award was established in 1992 by Audrey Butvay Gruss, an alumna of Jackson College. Working in the iBIT lab since last summer, Kelsey has been instrumental in helping with setting up the lab and the cell inventory for the lab. Read more about it here

04/16/2020

Paper Published in Particle!

First paper of the collaboration with Dr. Michelle Foster at UMass Boston is now published in Particle . Here we utilized novel nanoparticles for image-guided drug delivery

02/05/2020

Paper Published in JBO!

Our work on understanding mutual impact of dyes on photoacoustic contrast and photodynamic therapy is now published in Journal of Biomedical Optics!

10/19/2019

Recognition in IEEE Women in Photonics Magazine

Dr. Mallidi was recognized as the IEEE Women in Photonics Member of the month for her work in image-guided therapeutics, low cost photoacoustic imaging and photodynamic therapy (more…)

09/05/2019

Grad Students Chris & Marvin join the group

07/06/2019

Getting lab set up!

07/03/2019

Early Investigator Award at IPA

Dr. Mallidi wins the Early Investigator Award from the International Photodynamic Therapy Association. Checkout the various news channels on the award

 

07/01/2019

VisualSonics Travel Award

Harvard Research Tech Marvin Xavierselvan and Dr. Mallidi win the Travel Award from VisualSonics Inc and the Prestige People’s Choice Award at the IPA conference in Boston.

04/23/2019

First Grant to the iBIT Lab

First grant of the iBIT lab with Dr. Michelle Foster at University of Massachusetts Boston is funded. We are excited to work together on biodegradable nanoparticles for photodynamic therapy!

04/22/2019

Paper published in ACS Sensors!

04/21/2019

Visit to Wellman Labs

Wellman Lab visit with the BME 51/251 Class. Thank you Dr. Martin Villiger and Dr. Tayyaba Hasan lab for the time and resources to  make this trip possible.

03/26/2019

Lunch with Lab’s First co-op students

Celebrating the start of Spring and the lab- iBIT team first lunch gathering at Yoshi Restaurant.

02/03/2019

iBIT Lab at SPIE Photonics West

  • Marvin won the SPIE Student travel award!
  • Prof. Mallidi chaired a session in the Photodynamic Therapy Conference.

01/17/2019

Converging on Cancer At Tufts 2019 Meeting

Prof. Mallidi presented at the “Converging on Cancer at Tufts” Meeting, Tufts University, Medford MA

01/05/2019

UG Co-op students join lab

Brett Tierney, Tala Hefzi and Sarah Byron  join the lab as UG co-op students. They are currently a students at Wentworth Institute of Technology.

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