The research at the integrated Biofunctional Imaging and Therapeutics Laboratory (iBIT Lab) focuses on utilizing non-invasive acoustic and optical imaging techniques with nanomaterials and biological models to understand the structural, functional, molecular and biomechanical heterogeneity of pathologies such as cancer. The triangle in the iBIT lab logo depicts the three directions where biofunctional imaging will be utilized to improve patient care: 1. Guide surgical methods 2. Predict therapeutic response and 3. Design effective therapeutic strategies. We are a team of Biomedical engineers with interdisciplinary background in Electronics, signal processing, molecular biology, optics and nanotechnology with collaborations with clinicians and researchers in the Boston Area. We are always looking for enthusiastic highly motivated individuals to join our team.
We are actively looking for graduate students to join our Group. Students interested in non-invasive ultrasound and optical imaging with focus on image-guided therapies and cancer research, email Prof. Mallidi your CV. We also have openings for Postdoctoral fellows. Check out the current openings here.
05/18/2024
Congratulations to the iBIT Class of 2024!
05/06/2024
Jeanne defends her M.S. thesis!
05/03/2024
Valli wins the BEaChES BME Faculty Award!
05/03/2024
Capstone 2024 presents their poster titled “Breast Mimicking Phantoms to Decipher Skin Tone Bias and Penetration Depth Limit in Photoacoustic Imaging”
04/26/2024
Marvin wins the Outstanding Academic Scholarship Award from the Graduate School of Engineering!
04/25/2024
Chris defends his PhD dissertation!
04/12/2024
Vicky wins the De Flores Prize in Human Engineering and Patrick wins the Frederick M. and Dorie Ellis Prize!
04/03/2024
Skye wins 1st prize for their 3-minute talk “Quantitative ultrasound and photoacoustic imaging to monitor photodynamic therapy outcomes” at the Graduate Student Research Symposium!
02/23/2024
EP just dropped
01/29/2024
iBIT Attends SPIE Photonics West 2024
01/23/2024
Marvin defends his PhD dissertation!
11/06/2023
Andrew teaches about Photoacoustic Imaging and Brooke teaches about Nanoparticle Synthesis at the Reverse Science Fair at Medford High School
06/01/2023
Andrew Joins iBIT as a PhD Student!
The man himself is going to be stuck with us for the next 5 years *evil laugh*
05/21/2023
Jeanne Wins BME Senior of the Year
Congratulations on this amazing acheivement! We cant wait for you to join us as a Master’s student!
05/20/2023
Congratulations to the iBITers class of 2023!
04/28/2023
Andrew Wins De Florez Prize in Human Engineering and Howard Sample Prize in Physics!
04/28/2023
Valli Wins Engineering Faculty Mentorship Award
02/16/2023
Look at who’s on the internet – Patrick and Andrew
Check it out here
02/01/2023
iBIT takes SPIE Photonics West
Our lab visited San Fransisco to attend the SPIE Photonics West 2023 Conference! Chris, Skye, and Avijit gave great talks along with Marvin and Deeksha’s poster presentations! It was amazing to meet researchers from all over the world working on the development of Photoacoustic Imaging and Photodynamic Therapy.
12/14/2022
Holiday Celebration
The iBIT Team played Yankee Swap to celebrate the end of the year!
11/30/2022
SPIE Travel Awards
Congratulations to Avijit, Chris, and Deeksha who all received travel awards to present their research at the 2023 SPIE Photonics West Congress in San Fransisco.
11/18/2022
BME Research Retreat
Loved having the opportunity to share the research we do with the rest of the Tufts BME department
11/14/2022
Lab Potluck!
the jury is still out on who made the best biriyani 
09/09/2022
Optics Club Social
iBITers welcoming new graduate students at the Optics Club Social!
08/24/2022
Visit to Northeastern University!
Amazing gathering and scientific discussions happened today when the Optics groups of Tufts visited Northeastern
08/11/2022
TUBERS visit the lab!
Tufts University Biomedical Engineering Research Scholars (TUBERS) Program is for dedicated, academically-talented high school students. Some Tubers came to visit the lab and learn more about our research this summer!
08/05/2022
RO1 Grant Awarded!
Excited to share the news that we received R01 grant from the NIH National Cancer Institute to work on photoacoustic image-guided photodynamic therapy with nanodroplets to improve outcomes in head and neck cancer in collaboration with Nanohybrids Inc!
08/05/2022
End of Summer 2022 Lab Party
08/01/2022
Allison Passes Master’s Thesis Defense!
07/14/2022
Photoacoustic Monitoring of Suboptimal Therapy Efficacy
Just published from the iBIT Lab in the Frontiers in Oncology Cancer Imaging and Image-directed Interventions special issue. Read here
07/03/2022
Dr. Mallidi’s 40th Birthday
Happy Birthday Dr. Mallidi!
06/10/2022
UG students take over lab meeting!
06/08/2022
Skye, Deeksha, and Avijit Pass PhD Qualifiers!
06/01/2022
Marvin passes his ORP!
05/24/2022
NESS Translational Research Award
Congratulations to our very own Allison Sweeney for winning the New England Science Symposium’s Prophet Genomics Translational Research Award!
05/22/2022
Publication on Biodegradable Nanoparticles for PDT
Publication hot off the press from iBIT lab – Biodegradable Eutectic Gallium–Indium Nanoparticles fabricated via simple green sonication methods can be used for delivery of photosensitizers to the tumor for localized Photodynamic Therapy. Read here
05/20/2022
Congratulations to our Master’s Graduates
Congratulations to our Graduates! Special mention to Abigail Claus and Allison Sweeney, the first set of Master’s students to graduate from iBIT Lab! Abby is heading to Invicro and Allison decided to stay with us longer to research further on photoacoustics
05/15/2022
Allison Wins 2022 Pride on the Hill Award!
The award honors undergraduate or graduate students who, through community involvement, artistic expression, written work, or scientific research have contributed the most to an understanding at Tufts of gay, lesbian, bisexual, or trans identities during the preceding academic year.
05/13/2022
Grad Student Team
look at them go!
05/13/2022
Dr. Mallidi wins BEaChES Exemplary Engineer Award
The BME faculty recipient of this year’s award is Professor Srivalleesha Mallidi!
05/12/2022
BME Capstone Project Win
BME Capstone Best senior design project of the Year! Congratulations to these amazing young researchers in the Oudin Lab, and our very own Elli Diaz! 
04/21/2022
Abby Passes Master’s Thesis Defense
04/20/2022
Skye and Allison awarded at Tufts Graduate Student Research Symposium
04/13/2022
Mallidi named rising star
Dr. Mallidi has received a Rising Star Award from the World Molecular Imaging Congress. The award recognizes the contributions of outstanding women scientists in their early careers who demonstrate exceptional potential for contributions to the field of molecular imaging.
04/08/2022
Dr. Mallidi Speaks at Columbia
Dr. Mallidi presents on ultrasound guided photoacoustic imaging for treatment at Columbia’s BME Seminar Series. Watch here!
03/01/2022
R21 Grant Awarded
The iBIT Lab along with the Shelly Foster Group at UMASS Boston are the proud recipients of an R21 Grant!
03/01/2022
Chris passes his ORP!
02/02/2022
Vevo LAZR-X in Action!
11/20/2021
Lab Swag 🙂
09/06/2021
Jenny in action!
The histology queen is working hard
09/02/2021
Light on Tissue!
Light on Tissue cool stuff happening in lab!
08/20/2021
Allison and Abby pass Master’s ORP
Congrats to the iBIT Lab’s first Master’s students!
08/06/2021
2021 Tubers Summer Program
Local high school students come to tour the lab and learn about the science we do!
09/05/2020
Publication on Frontiers in Placenta Imaging
Checkout our review paper here, headed by Chris Nguyen, on placenta imaging with Dr. Mary Wallingford group! We are excited about this collaboration and new directions for photoacoustic and photodynamic therapy!
08/14/2020
Study on LED-Photoacoustic Imaging for imaging tumor vasculature is now published
Access paper here. Traditionally photoacoustic systems employ expensive and bulky class IV lasers with low pulse repetition rate, due to which its availability for preclinical cancer research is hampered. In this study, we evaluated the capability of a Light-Emitting Diode (LED)-based PA and ultrasound (US) imaging system for monitoring heterogeneous microvasculature in tumors (up to 10 mm in depth) and quantitatively compared the PA images with gold standard histology images. Analysis of 30 regions of interest in tumors from different mice showed a statistically significant R-value of 0.84 where the areas with high blood vessel density had high PA response while low blood vessel density regions had low PA response. Our results confirm that LED-based PA and US imaging can provide 2D and 3D images of tumor vasculature and the potential it has as a valuable tool for preclinical cancer research.
07/16/2020
Imaging equipment is here!
The Vevo LAZR-X ultrasound and photoacoustic imaging system is here! We recently received NIH funds to purchase this equipment. We cannot wait for the labs to fully reopen to hook this system up and look inside of tumors!
07/07/2020
New iBIT Lab publication
Does angle of illumination really matter in LED based photoacoustic imaging for deep tumor imaging? Check out our new publication here in Sensors that answers this question with 3D printed flexible angle holder!
06/14/2020
NIH S10 Award for Dr. Mallidi
Dr. Mallidi has received an S10 award to setup a small animal imaging core at the Medford Campus! The first instrument in the core is FujiFILM VisualSonics Ultrasound and photoacoustic imaging instrument
06/05/2020
Chris & Marvin pass Qualifiers
iBIT Labs first batch of graduate students- Chris Nguyen and Marvin Xavierselvan pass the PhD qualifiers! Congratulations!
05/22/2020
Paper published in JSR
Our work with Redmond team at MGH is now published in JSR. We showcase the utility of high frequency ultrasound imaging in cardiovascular research – particularly to measure intima/media thickness and blood flow in diseased and treated Pig vessels in vivo. Read the paper here
05/06/2020
We are on Tufts NEWS!
04/21/2020
UG Kelsey Detels wins the Audrey Butvavy Gruss Science Award
Congratulations Kelsey!She won the Audrey Butvavy Gruss Science Award for Juniors/seniors for the year 2020. Awarded annually to a student who has demonstrated outstanding academic work in any of the sciences and who is a scholarship recipient. This award was established in 1992 by Audrey Butvay Gruss, an alumna of Jackson College. Working in the iBIT lab since last summer, Kelsey has been instrumental in helping with setting up the lab and the cell inventory for the lab. Read more about it here
04/16/2020
Paper Published in Particle!
First paper of the collaboration with Dr. Michelle Foster at UMass Boston is now published in Particle . Here we utilized novel nanoparticles for image-guided drug delivery
02/05/2020
Paper Published in JBO!
Our work on understanding mutual impact of dyes on photoacoustic contrast and photodynamic therapy is now published in Journal of Biomedical Optics!
10/19/2019
Recognition in IEEE Women in Photonics Magazine
Dr. Mallidi was recognized as the IEEE Women in Photonics Member of the month for her work in image-guided therapeutics, low cost photoacoustic imaging and photodynamic therapy (more…)
09/05/2019
Grad Students Chris & Marvin join the group
07/06/2019
Getting lab set up!
07/03/2019
Early Investigator Award at IPA
Dr. Mallidi wins the Early Investigator Award from the International Photodynamic Therapy Association. Checkout the various news channels on the award
07/01/2019
VisualSonics Travel Award
Harvard Research Tech Marvin Xavierselvan and Dr. Mallidi win the Travel Award from VisualSonics Inc and the Prestige People’s Choice Award at the IPA conference in Boston.
04/23/2019
First Grant to the iBIT Lab
First grant of the iBIT lab with Dr. Michelle Foster at University of Massachusetts Boston is funded. We are excited to work together on biodegradable nanoparticles for photodynamic therapy!
04/22/2019
Paper published in ACS Sensors!
- Check out our recent publication in ACS Sensors – photoacoustic imaging of DNA nanosensors with Prof. Heather Clark at Northeastern University.
04/21/2019
Visit to Wellman Labs
Wellman Lab visit with the BME 51/251 Class. Thank you Dr. Martin Villiger and Dr. Tayyaba Hasan lab for the time and resources to make this trip possible.
03/26/2019
Lunch with Lab’s First co-op students
Celebrating the start of Spring and the lab- iBIT team first lunch gathering at Yoshi Restaurant.
02/03/2019
iBIT Lab at SPIE Photonics West
- Marvin won the SPIE Student travel award!
- Prof. Mallidi chaired a session in the Photodynamic Therapy Conference.
01/17/2019
Converging on Cancer At Tufts 2019 Meeting
Prof. Mallidi presented at the “Converging on Cancer at Tufts” Meeting, Tufts University, Medford MA
01/05/2019
UG Co-op students join lab
Brett Tierney, Tala Hefzi and Sarah Byron join the lab as UG co-op students. They are currently a students at Wentworth Institute of Technology.
