⊗ = undergraduate; † = equal contributions; * = corresponding author(s)

Work done at Tufts

1. T. C. Chappell, T. B. Nicks, J.-F. Cheng, A. Tarver, J. A. Lee, A. Kalia⊗, N. U. Nair*, “Advancing Protein Display on Bacterial Spores Through an Extensive Survey of Coat Components”, bioRxiv (link) (under review)
2. J. Dolgin†, D. Chakravarty†, S. F. Sullivan, Y. Cai, T. Lim, P. Yamaguchi, J. E. Balkan⊗, L. Xu, A. D. Olawoyin⊗, K. Lee, D. L. Kaplan, N. U. Nair*, “Microbial Lysates As Low-cost Serum Replacements in Cellular Agriculture Media Formulation”, bioRxiv (link) (under review)
3. T. C. Chappell, K. G. Maiello, A. J. Tierney, K. Yanagi, J. A. Lee, K. Lee, C. R. Mace, C. S. Bennett, N. U. Nair*, “Rapid Spectrophotometric Detection for Optimized Production of Landomycins and Characterization of Their Therapeutic Potential”, Biotechnology & Bioengineering, 2024 (link, bioRxiv, PMC)
4. A. M. Love, N. U. Nair*, “Specific Codons Control Cellular Resources and Fitness”, Science Advances, 2024 (link, bioRxiv, PMC)
   Associated press release: School of Engineering News
5. S. F. Sullivan, A. Shetty, T. Bharadwaj, N. Krishna, V. D. Trivedi, V. Endalur Gopinarayanan, D. M. Sellers, P. Kumar R. N. U. Nair*,  “Towards Universal Synthetic Heterotrophy Using a Metabolic Coordinator”, Metabolic Engineering, 2023 (link, bioRxiv, PMC)
   Associated publication: Tufts Now
6. V. D. Trivedi, S. F. Sullivan, D. Choudhury, V. Endalur Gopinarayanan, T. Hart⊗, N. U. Nair*, “Integration of Metabolism and Regulation Reveals Rapid Adaptability to Growth on Non-native Substrates”, Cell Chemical Biology, 2023 (link, bioRxiv, PMC)
   Associated publication: Tufts Now
7. M. Lei, V. D. Trivedi, N. U. Nair, K. Lee*, J. A. Van Deventer*, “Flow Cytometric Evaluation of Yeast-Bacterial Cell-Cell Interactions”, Biotechnology & Bioengineering, 2023 (link, PMC)
8. L. d’Amone†, V. D. Trivedi†, N. U. Nair*, F. G. Omonetto*, “A Silk-based Platform to Stabilize Phenylalanine Ammonia-Lyase (PAL) for Orally Administered Enzyme Replacement Therapy”, Molecular Pharmaceutics, 2022 (link, PMC)
   Associated publications: Drug Discovery News
9. R. Said†, Z. J. S. Mays†, N. U. Nair*, “Modulating Residence Time and Biogeography of Engineered Probiotics”, Book Chapter in Principles of Microbiome Engineering, M. W. Chang (ed.), Wiley Publishing, 2022 (link)
10. V. D. Trivedi†, T. C. Chappell†, N. B. Krishna, A. Shetty, G. G. Sigamani, K. Mohan, A. Ramesh⊗, P. Kumar R., N. U. Nair*, “In-depth Sequence-Function Characterization Reveals Multiple Pathways to Enhance Enzymatic Activity”, ACS Catalysis, 2022 (link, PMC)
    Associated press release: School of Engineering News
11. V. D Trivedi, K. Mohan, T. C. Chappell, Z. J. S. Mays, N. U. Nair*, “Cheating the Cheater: Suppressing False Positive Enrichment During Biosensor-Guided Biocatalyst Engineering”, ACS Synthetic Biology, 2022 (link, PMC)
12. V. Porokhin, S. A. Amin, T. B. Nicks, V. Endalur Gopinaryanan, N. U. Nair*, S. Hassoun*, “Analysis of Metabolic Network Disruption in Engineered Microbial Hosts Due to Enzyme Promiscuity”, Metabolic Engineering Communication, 2021 (link, PMC)
13. Z. J. S. Mays, N. U. Nair*, “A Quantitative Model for Metabolic Intervention using Gut Microbes”, Biotechnology Progress, 2021 (link, PMC)
14. T. C. Chappell, N. U. Nair*, “Engineered Lactobacilli Display Anti-Biofilm and Growth Suppressing Activities Against Pseudomonas aeruginosa“, npj Biofilms & Microbiomes, 2020 (link, PMC)
15. B. Motta Nascimento, N. U. Nair, “Characterization of a Membrane Enzymatic Complex for Heterologous Production of Poly-γ-glutamate in E. coli“, Metabolic Engineering Communications, 2020 (link, PMC)
16. Z. J. S. Mays†, K. Mohan†, V. D. Trivedi, T. C. Chappell, N. U. Nair*, “Directed Evolution of Anabaena variabilis Phenylalanine Ammonia-Lyase (PAL) Identifies Mutants with Enhanced Activities”, Chemical Communications, 2020 (link, PMC)
    Associated press release: School of Engineering News
17. Z. J. S. Mays, T. C. Chappell, N. U. Nair*, “Quantifying and Engineering Mucus Adhesion of Probiotics”, ACS Synthetic Biology, 2020 (link, PMC)
18. J. R. Bober, N. U. Nair*, “Galactose to Tagatose Isomerization at Moderate Temperatures with High Conversion and Productivity” Nature Communications, 2019 (link, PMC)
    Associated press releases and news articles: Tufts Now!, Reddit
19. S. A. Amin†, E. Chavez†⊗, V. Porokhin⊗, N. U. Nair*, S. Hassoun*, “Towards Creating an Extended Metabolic Model (EMM) for E. coli Using Enzyme Promiscuity Prediction and Metabolomics Data”, Microbial Cell Factories, 2019 (link, PMC)
20. S. A. Amin, V. Endalur Gopinarayanan, N. U. Nair*, S. Hassoun*, “Establishing Synthesis Pathway-Host Compatibility via Enzyme Solubility”, Biotechnology & Bioengineering, 2019 (link, PMC)
21. V. Endalur Gopinarayanan, N. U. Nair*, “Pentose Metabolism in Saccharomyces cerevisiae: The Need to Engineer Global Regulatory Systems”, Biotechnology Journal (perspective & review), 2019 (link, PMC)
22. V. Endalur Gopinarayanan, N. U. Nair*, “A Semi-synthetic Regulon Enables Rapid Growth of Yeast on Xylose”, Nature Communications, 2018 (link, PMC)
    Associated press releases and news articles: Tufts Now!, Biofuels International, EurekAlert!, NewsWise, and MediaNet.
23. J. R. Bober, C. L. Beisel*, N. U. Nair*, “Synthetic Biology Approaches to Engineer Probiotics and Members of the Human Microbiota for Biomedical Applications”, Annual Review of Biomedical Engineering, 2018 (link, PMC)
24. Z. J. S. Mays, N. U. Nair*, “Synthetic Biology in Probiotic Lactic Acid Bacteria: At the Frontier of Living Therapeutics”, Current Opinion in Biotechnology, 2018 (link, PMC)
25. M. Waller, J. R. Bober, N. U. Nair, C. L. Beisel*, “Toward a Genetic Tool Development Pipeline for Host-associated Bacteria”, Current Opinion in Microbiology, 2017 (link, PMC)
26. T. C. Chappell, N. U. Nair*, “Co-utilization of Hexoses by a Microconsortium of Sugar-Specific E. coli Strains”, Biotechnology & Bioengineering, 2017 (link)
27. J. I. Marcus⊗, S. Hassoun, N. U. Nair*, “Computational Prediction of Functional Abortive RNA in E. coli“, Genomics, 2017 (link)
28. N. Hassanpour, E. Ullah, M. Yousofshahi, N. U. Nair, S. Hassoun*, “Selection Finder (SelFi): A Computational Metabolic Engineering Tool to Enable Directed Evolution of Enzymes”, Metabolic Engineering Communications, 2017 (link, PMC)
    

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    Work done before joining Tufts

29. S. R. Goldman†, N. U. Nair†, C. D. Wells, B. E. Nickels*, A. Hochschild*, “The Primary σ Factor in Escherichia coli Can Access the Transcription Elongation Complex from Solution in vivo”, eLife, 2015 (link)
30. J. Lian, T. Si, N. U. Nair, H. Zhao*, “Design and Construction of Acetyl-CoA Overproducing Saccharomyces cerevisiae Strains”, Metabolic Engineering, 2014 (link)
31. J. Sun, Z. Shao, H. Zhao, N. U. Nair, F. Wen, J.H. Xu, H. Zhao*, “Cloning and Characterization of a Panel of Constitutive Promoters for Applications in Pathway Engineering in Saccharomyces cerevisiae“, Biotechnology & Bioengineering, 2012 (link)
32. Y. Zou, H. Zhang, T. W. Johannes, R. D. Woodyer, N. U. Nair, J. S. Bruznelle, W. van der Donk, H. Zhao, S. K. Nair*, “Crystal Structures of Phosphite Dehydrogenase Provide Insights into Nicotinamide Cofactor Regeneration”, Biochemistry, 2012 (link)
33. N. U. Nair, H. Zhao*, “Selective Reduction of Xylose to Xylitol from a Mixture of Hemicellulosic Sugars”, Metabolic Engineering, 2010 (link)
34. N. U. Nair, W. L. Tang, D. E. Eriksen, H. Zhao*, “Industrial Applications of Enzymes as Catalysts”, Manual of Industrial Microbiology and Biotechnology (3rd edition), R. H. Baltz, J. E. Davies, A. L. Demain (editors), ASM Press, 2010 (link1, link2)
35. C. A. Denard, N. U. Nair, H. Zhao*, “Engineering of Enzymes for Selective Catalysis”, Current Organic Chemistry, 2010 (link)
36. F. Wen, N. U. Nair, H. Zhao*, “Protein Engineering in Designing Tailored Enzymes and Microorganisms for Biofuels Production” Current Opinion in Biotechnology, 2009 (link)
37. N. U. Nair, H. Zhao*, “Improving Protein Function by Directed Evolution”, The Metabolic Pathway Engineering Handbook, C. D. Smolke (editor) CRC Press, 2009 (link)
38. N. U. Nair, H. Zhao*, “Mutagenic Inverted Repeat Assisted Genome Engineering (MIRAGE)”, Nucleic Acids Research, 2009 (link)
39. N. U. Nair, H. Zhao*, “Evolution in Reverse: Engineering a D-Xylose-specific Xylose Reductase”, ChemBioChem, 2008 (link)
40. N. U. Nair, H. Zhao*, “Biochemical Characterization of an L-Xylulose Reductase from Neurospora crassa“, Applied & Environmental Microbiology, 2007 (link)

Dr. Nair’s publications can also be found on Google Scholar and NCBI’s MyBibliography.