⊗ = undergraduate; † = equal contributions; * = corresponding author(s)
Work done at Tufts
- V. D. Trivedi, T. C. Chappell, N. U. Nair* (in preparation)
- V. D. Trivedi, N. U. Nair*, (in preparation)
- T. C. Chappell, T. B. Nicks. J-F. Cheng, A. Tarver, J. A. Lee, A. Kalia⊗, N. U. Nair* (in preparation)
- T. C. Chappell, K. G. Maiello, A. J. Tierney, K. Yanagi, J. A. Lee, K. Lee, C. R. Mace, C. S. Bennett, N. U. Nair*, “Rapid Spectrophotometric Detection for Optimized Production of Landomycins and Characterization of Their Therapeutic Potential”, Biotechnology & Bioengineering, 2024 (link, bioRxiv, PMC)
- A. M. Love, N. U. Nair*, “Specific Codons Control Cellular Resources and Fitness”, Science Advances, 2024 (link, bioRxiv, PMC)
Associated press release: School of Engineering News - S. F. Sullivan, A. Shetty, T. Bharadwaj, N. Krishna, V. D. Trivedi, V. Endalur Gopinarayanan, D. M. Sellers, P. Kumar R. N. U. Nair*, “Towards Universal Synthetic Heterotrophy Using a Metabolic Coordinator”, Metabolic Engineering, 2023 (link, bioRxiv, PMC)
Associated publication: Tufts Now - V. D. Trivedi, S. F. Sullivan, D. Choudhury, V. Endalur Gopinarayanan, T. Hart⊗, N. U. Nair*, “Integration of Metabolism and Regulation Reveals Rapid Adaptability to Growth on Non-native Substrates”, Cell Chemical Biology, 2023 (link, bioRxiv, PMC)
Associated publication: Tufts Now - M. Lei, V. D. Trivedi, N. U. Nair, K. Lee*, J. A. Van Deventer*, “Flow Cytometric Evaluation of Yeast-Bacterial Cell-Cell Interactions”, Biotechnology & Bioengineering, 2023 (link, PMC)
- L. d’Amone†, V. D. Trivedi†, N. U. Nair*, F. G. Omonetto*, “A Silk-based Platform to Stabilize Phenylalanine Ammonia-Lyase (PAL) for Orally Administered Enzyme Replacement Therapy”, Molecular Pharmaceutics, 2022 (link, PMC)
Associated publications: Drug Discovery News - R. Said†, Z. J. S. Mays†, N. U. Nair*, “Modulating Residence Time and Biogeography of Engineered Probiotics”, Book Chapter in Principles of Microbiome Engineering, M. W. Chang (ed.), Wiley Publishing, 2022 (link)
- V. D. Trivedi†, T. C. Chappell†, N. B. Krishna, A. Shetty, G. G. Sigamani, K. Mohan, A. Ramesh⊗, P. Kumar R., N. U. Nair*, “In-depth Sequence-Function Characterization Reveals Multiple Pathways to Enhance Enzymatic Activity”, ACS Catalysis, 2022 (link, PMC)
Associated press release: School of Engineering News - V. D Trivedi, K. Mohan, T. C. Chappell, Z. J. S. Mays, N. U. Nair*, “Cheating the Cheater: Suppressing False Positive Enrichment During Biosensor-Guided Biocatalyst Engineering”, ACS Synthetic Biology, 2022 (link, PMC)
- V. Porokhin, S. A. Amin, T. B. Nicks, V. Endalur Gopinaryanan, N. U. Nair*, S. Hassoun*, “Analysis of Metabolic Network Disruption in Engineered Microbial Hosts Due to Enzyme Promiscuity”, Metabolic Engineering Communication, 2021 (link, PMC)
- Z. J. S. Mays, N. U. Nair*, “A Quantitative Model for Metabolic Intervention using Gut Microbes”, Biotechnology Progress, 2021 (link, PMC)
- T. C. Chappell, N. U. Nair*, “Engineered Lactobacilli Display Anti-Biofilm and Growth Suppressing Activities Against Pseudomonas aeruginosa“, npj Biofilms & Microbiomes, 2020 (link, PMC)
- B. Motta Nascimento, N. U. Nair, “Characterization of a Membrane Enzymatic Complex for Heterologous Production of Poly-γ-glutamate in E. coli“, Metabolic Engineering Communications, 2020 (link, PMC)
- Z. J. S. Mays†, K. Mohan†, V. D. Trivedi, T. C. Chappell, N. U. Nair*, “Directed Evolution of Anabaena variabilis Phenylalanine Ammonia-Lyase (PAL) Identifies Mutants with Enhanced Activities”, Chemical Communications, 2020 (link, PMC)
Associated press release: School of Engineering News - Z. J. S. Mays, T. C. Chappell, N. U. Nair*, “Quantifying and Engineering Mucus Adhesion of Probiotics”, ACS Synthetic Biology, 2020 (link, PMC)
- J. R. Bober, N. U. Nair*, “Galactose to Tagatose Isomerization at Moderate Temperatures with High Conversion and Productivity” Nature Communications, 2019 (link, PMC)
Associated press releases and news articles: Tufts Now!, Reddit - S. A. Amin†, E. Chavez†⊗, V. Porokhin⊗, N. U. Nair*, S. Hassoun*, “Towards Creating an Extended Metabolic Model (EMM) for E. coli Using Enzyme Promiscuity Prediction and Metabolomics Data”, Microbial Cell Factories, 2019 (link, PMC)
- S. A. Amin, V. Endalur Gopinarayanan, N. U. Nair*, S. Hassoun*, “Establishing Synthesis Pathway-Host Compatibility via Enzyme Solubility”, Biotechnology & Bioengineering, 2019 (link, PMC)
- V. Endalur Gopinarayanan, N. U. Nair*, “Pentose Metabolism in Saccharomyces cerevisiae: The Need to Engineer Global Regulatory Systems”, Biotechnology Journal (perspective & review), 2019 (link, PMC)
- V. Endalur Gopinarayanan, N. U. Nair*, “A Semi-synthetic Regulon Enables Rapid Growth of Yeast on Xylose”, Nature Communications, 2018 (link, PMC)
Associated press releases and news articles: Tufts Now!, Biofuels International, EurekAlert!, NewsWise, and MediaNet. - J. R. Bober, C. L. Beisel*, N. U. Nair*, “Synthetic Biology Approaches to Engineer Probiotics and Members of the Human Microbiota for Biomedical Applications”, Annual Review of Biomedical Engineering, 2018 (link, PMC)
- Z. J. S. Mays, N. U. Nair*, “Synthetic Biology in Probiotic Lactic Acid Bacteria: At the Frontier of Living Therapeutics”, Current Opinion in Biotechnology, 2018 (link, PMC)
- M. Waller, J. R. Bober, N. U. Nair, C. L. Beisel*, “Toward a Genetic Tool Development Pipeline for Host-associated Bacteria”, Current Opinion in Microbiology, 2017 (link, PMC)
- T. C. Chappell, N. U. Nair*, “Co-utilization of Hexoses by a Microconsortium of Sugar-Specific E. coli Strains”, Biotechnology & Bioengineering, 2017 (link)
- J. I. Marcus⊗, S. Hassoun, N. U. Nair*, “Computational Prediction of Functional Abortive RNA in E. coli“, Genomics, 2017 (link)
- N. Hassanpour, E. Ullah, M. Yousofshahi, N. U. Nair, S. Hassoun*, “Selection Finder (SelFi): A Computational Metabolic Engineering Tool to Enable Directed Evolution of Enzymes”, Metabolic Engineering Communications, 2017 (link, PMC)
Work done before joining Tufts
- S. R. Goldman†, N. U. Nair†, C. D. Wells, B. E. Nickels*, A. Hochschild*, “The Primary σ Factor in Escherichia coli Can Access the Transcription Elongation Complex from Solution in vivo”, eLife, 2015 (link)
- J. Lian, T. Si, N. U. Nair, H. Zhao*, “Design and Construction of Acetyl-CoA Overproducing Saccharomyces cerevisiae Strains”, Metabolic Engineering, 2014 (link)
- J. Sun, Z. Shao, H. Zhao, N. U. Nair, F. Wen, J.H. Xu, H. Zhao*, “Cloning and Characterization of a Panel of Constitutive Promoters for Applications in Pathway Engineering in Saccharomyces cerevisiae“, Biotechnology & Bioengineering, 2012 (link)
- Y. Zou, H. Zhang, T. W. Johannes, R. D. Woodyer, N. U. Nair, J. S. Bruznelle, W. van der Donk, H. Zhao, S. K. Nair*, “Crystal Structures of Phosphite Dehydrogenase Provide Insights into Nicotinamide Cofactor Regeneration”, Biochemistry, 2012 (link)
- N. U. Nair, H. Zhao*, “Selective Reduction of Xylose to Xylitol from a Mixture of Hemicellulosic Sugars”, Metabolic Engineering, 2010 (link)
- N. U. Nair, W. L. Tang, D. E. Eriksen, H. Zhao*, “Industrial Applications of Enzymes as Catalysts”, Manual of Industrial Microbiology and Biotechnology (3rd edition), R. H. Baltz, J. E. Davies, A. L. Demain (editors), ASM Press, 2010 (link1, link2)
- C. A. Denard, N. U. Nair, H. Zhao*, “Engineering of Enzymes for Selective Catalysis”, Current Organic Chemistry, 2010 (link)
- F. Wen, N. U. Nair, H. Zhao*, “Protein Engineering in Designing Tailored Enzymes and Microorganisms for Biofuels Production” Current Opinion in Biotechnology, 2009 (link)
- N. U. Nair, H. Zhao*, “Improving Protein Function by Directed Evolution”, The Metabolic Pathway Engineering Handbook, C. D. Smolke (editor) CRC Press, 2009 (link)
- N. U. Nair, H. Zhao*, “Mutagenic Inverted Repeat Assisted Genome Engineering (MIRAGE)”, Nucleic Acids Research, 2009 (link)
- N. U. Nair, H. Zhao*, “Evolution in Reverse: Engineering a D-Xylose-specific Xylose Reductase”, ChemBioChem, 2008 (link)
- N. U. Nair, H. Zhao*, “Biochemical Characterization of an L-Xylulose Reductase from Neurospora crassa“, Applied & Environmental Microbiology, 2007 (link)
Dr. Nair’s publications can also be found on Google Scholar and NCBI’s MyBibliography.