Tufts Peptides Promote Wound Healing in Diabetic Swine

Investigators at Tufts Center for Innovations in Wound Healing have recently reported that two bioactive peptides invented markedly promote wound healing in diabetic swine. The study carried out by a team of physicians and scientists at Tufts University’s School of Medicine and Tufts Medical Center demonstrate that the wound healing peptides convert non-healing wounds into those capable of closure by activating wound healing angiogenesis, promoting epidermal cell migration and growth while ‘re-balancing’ the wound bed’s protease and protease inhibitor profiles.  The work, which recently published in the Journal of Translational Medicine (JTM) follows earlier work demonstrating safety and efficacy in cell-based assays and in murine models of impaired healing. A link to the JTM publication can be found here: Sheets et al, 2016

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