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Ira Herman

American Journal of Physiology Paper of the Year Award

APSAwards Recently, at Experimental Biology 2015 being held in Boston, MA. Jennifer Durham received honors for ‘Pericyte contractility controls endothelial cell cycle progression and sprouting: Insights into angiogenic switch mechanics’, which we published late last year. The work, which teaches how pericyte chemo-mechanics controls endothelial growth dynamics and angiogenic switching, not only represents a major […]

Center Director delivers Henry Stewart Talk, entitled ‘Dynamic Reciprocity and Wound Healing’

Professor Herman recently delivered a Henry Stewart Talk (HST) on dynamic reciprocity and wound healing.  A link to the HST can be found here:

Insights into Angiogenic Switch Mechanics: A Role for Microvascular Pericytes in Wound Healing

Recent work ongoing in the Center for Innovations in Wound Healing Research now indicates that microvascular pericytes can ‘instruct’ capillary-derived endothelial cells, ‘switching’ the endothelium from a growth-arrested into a growth-promoted state.  With this shift, there is a marked increase in angiogenic potential when specific features of the pericyte are altered via genetic and molecular […]

Center Director Interview – Wound Healing Peptides and Therapeutic Innovation

Recently, Ira Herman was interviewed about the therapeutic potential of the wound healing peptides created at Tufts University’s Center for Innovations in Wound Healing Research.  Here is the YouTube link to the interview with Professor Herman

Pericytes are protective for retinal microvessels

In a recent study, work ongoing in TIWR in collaboration with colleagues at the University of Virginia indicates that a vascular progenitor cell population derived from adipose is capable of protecting the retinal capillaries against the damaging effects of elevated oxygen. These pre-clinical findings lend strong support for the notion that pericyte-like cells derived from […]

TIWR Director to present at the Alliance for Regenerative Medicine

 ‘Clinical Outlooks for Regenerative Medicine’, which was held in Boston, MA on June 19, 2012, was a remarkable event.. bringing industry and academic leaders together for an exciting program. From the Alliance for Regenerative Medicine Meeting Website: “As many regenerative medicine and cell therapy products move into clinical trials, a clearer understanding of how these […]

Bioactive Wound Healing Peptides Promote Wound Healing In Vivo

Recent work from the Tufts Center for Innovations in Wound Healing Research has revealed that two novel peptides combine to synergistically accelerate wound healing using an in vivo model of impaired healing.  This work was recently published in PLoS One ( ) and was recently covered globally ( )

Speeding Up The Healing Process

Work ongoing at the Center for Innovations in Wound Healing Research was recently highlighted in Technology Review

The Dynamics of Wound Healing

Recent work reveals that wound healing dynamics are tightly and reciprocally regulated. In particular, cellular components within the epidermal and dermal wound microenvironments transduce signals that control extracellular matrix remodeling and wound healing dynamics. In turn, these cellular and extracellular signaling cascades control whether or to what extent wound repair progresses or is chronically impaired. […]

Bioactive Peptides Promote Wound Healing

Newly-created bioactive peptides promote wound healing through the growth of new blood vessels and epithelial tissue, such as skin. These wound-healing peptides, synthesized by researchers at the Tufts Center for Innovations in Wound Healing Research promote re-epithelialization and wound healing angiogenesis as reported online in Wound Repair and Regeneration News Release News Release