Selected Research Publications:
Tissue Engineering:
Bioengineered functional brain-like cortical tissue.
Tang-Schomer et al. PNAS 111: 13811-6 (2014).
In vitro bioengineered model of cortical brain tissue.
Chwalek et al. Nature Protocols 10: 1362-73 (2015).
Expandable and rapidly differentiating human induced neural stem cell lines for multiple tissue engineering applications.
Cairns et al. Stem Cell Reports 7: 557-70 (2016).
Fetal brain extracellular matrix boosts neuronal network formation in 3D bioengineered model of cortical brain tissue.
Sood et al. ACS Biomater Sci Eng. 2: 131-40 (2016).
Human endothelial cells secrete neurotropic factors to direct axonal growth of peripheral nerves.
Grasman & Kaplan. Sci Rep. 7: 4092 (2017).
Endogenous two-photon excited fluorescence imaging characterizes neuron and astrocyte metabolic responses to manganese toxicity.
Stuntz et al. Sci Rep. 7: 1041 (2017).
In vitro 3D regeneration-like growth of human patient brain tissue.
Tang-Schomer et al. J Tissue Eng Regen Med. 12: 1247-60 (2018).
Niclosamide rescues microcephaly in a humanized in vivo model of Zika infection using human induced neural stem cells.
Cairns et al. Biol Open 7: 1 (2018).
Bioinspired three-dimensional human neuromuscular junction development in suspended hydrogel arrays.
Dixon et al. Tissue Eng Part C Methods 24: 346-359 (2018).
Functional and sustainable 3D human neural network models from pluripotent stem cells.
Cantley et al. ACS Biomater Sci Eng. 4: 4278-88 (2018).
Tissue models for neurogenesis and repair in 3D.
Grasman et al. Advanced Functional Materials 28: 1803822 (2018).
Ivermectin promotes peripheral nerve regeneration during wound healing.
Cairns et al. ACS Omega 3: 12392-402 (2018).
Engineering advanced neural tissue constructs to mitigate acute cerebral inflammation after brain transplantation in rats.
Liaudanskya et al. Biomaterials 192: 510-22 (2019).