We are interested in unraveling the mechanisms that viruses use to take control of infected cells and in particular reprogram host gene expression to promote the viral life cycle.
The infectious agent at the centers of our studies are an AIDS-related pathogen, Kaposi’s sarcoma-associated herpesvirus (KSHV), which causes Kaposi’s sarcoma and aggressive lymphomas, and the ubiquitous influenza A virus. Kaposi’s sarcoma remains the major cause of cancer-related death in parts of Africa and there are no targeted therapies for this disease. Influenza A virus infections affect 5-15% of the world-wide population yearly, with up to half a million deaths per year. Vaccines and therapeutic options are still only partly effective.
Understanding the biology of KSHV and influenza A virus will help in the design new therapeutic strategies. Also, studying the complex interaction of viral and cellular factors allows us to probe the normal working of the cell and uncover fundamental new aspects of gene regulation.
Interested in joining?
We are hiring! – we are looking for a senior research assistant that will work on one or more research projects under the direction of the PI, and will also contribute to the administrative aspects of running the lab and to mentoring junior members of the laboratory.
We are looking for a dynamic, enthusiastic and motivated person, someone who embraces a challenge, has strong critical thinking, is comfortable switching project if needed, understands and implements high standards of lab practice, and is able to work well within a team. The lab environment is collaborative and friendly, and we are committed to diversity. The position is currently for 1 year limited term, with the potential of extension. Please contact Dr. Gaglia at Marta.Gaglia@tufts.edu and/or submit an application through Tufts website http://tufts.taleo.net/careersection/jobdetail.ftl?job=18001793&lang=en#.XEd97b8Au_U.mailto if interested.
Students: We are affiliated with the graduate programs in Molecular Microbiology, Immunology and CMDB program at the Sackler School for Graduate Biomedical Sciences at Tufts University. We also have summer undergraduates through the BDBS summer program and post-bac interns through the PREP program. Apply here. Also contact Dr. Gaglia directly at Marta.Gaglia@tufts.edu if you are interested in a position as summer/undergraduate intern (not through BDBS).
Post-docs: We are always looking for talented and dynamic people to join our team! Please contact Dr. Gaglia at Marta.Gaglia@tufts.edu if interested.