INSciDE Research Presented at Annual Meetings and International Conferences
The latest work of the INSciDE team was presented by Marly Coe, Liam Power, and Peter Hsi at the annual meetings for the Biomedical Engineering Society, Tissue Engineering and Regenerative Medicine International Society, and American Association of Extracellular Vesicles as well as internationally at the Cerebral Vascular Biology Conference and Advances in 3D Bioprinting Conference. They presented on our 3D human brain-like tissue models of neuro-regeneration after traumatic brain injury, scaffold models of blood-brain barrier to examine mechanisms of chronic damage, and using extracellular vesicles to gain insight into TBI progression.
To see a full list of INSciDE conference presentations, click here.
Latest Research from the INSciDE Team Published in Scientific Journals
Several papers on INSciDE research were recently published in Cell Death & Disease, Molecular Psychiatry, Biomaterials, Nature Reviews Bioengineering, Journal of Neuroscience Research, and Journal of Alzheimer’s Disease. These papers include the latest advances in utilizing our 3D bioengineered brain-like tissues as models for studying neurodegeneration, traumatic brain injury, Alzheimer’s and Parkinson’s disease. To read the papers, click on the links below:
- Mitochondria dysregulation contributes to secondary neurodegeneration progression post-contusion injury in human 3D in vitro triculture brain tissue model
- Volha Liaudanskaya, Nicholas J. Fiore, Yang Zhang, Yuka Milton, Marilyn F. Kelly, Marly Coe, Ariana Barreiro, Victoria K. Rose, Matthew R. Shapiro, Adam S. Mullis, Anna Shevzov-Zebrun, Mathew Blurton-Jones, Michael J. Whalen, Aviva J. Symes, Irene Georgakoudi, Thomas J.F. Nieland, and David L. Kaplan. Cell Death & Disease (2023).
- 3D bioengineered neural tissue generated from patient-derived iPSCs mimics time-dependent phenotypes and transcriptional features of Alzheimer’s disease
- Selene Lomoio, Ravi S. Pandey, Nicolas Rouleau, Beatrice Menicacci, WonHee Kim, William L. Cantley, Philip G. Haydon, David A. Bennett, Tracy L. Young-Pearse, Gregory W. Carter, David L. Kaplan, and Giuseppina Tesco. Molecular Psychiatry (2023).
- Functional bioengineered tissue models of neurodegenerative diseases
- Adam S. Mullis and David L. Kaplan. Biomaterials (2023).
- Functional bioengineered models of the central nervous system
- Nicolas Rouleau, Nirosha J. Murugan, and David L. Kaplan. Nature Reviews Bioengineering (2023).
- Development of a novel bioengineered 3D brain-like tissue for studying primary blast-induced traumatic brain injury
- Dustin M. Snapper, Bianca Reginauld, Volha Liaudanskaya, Vincent Fitzpatrick, Yeonho Kim, Irene Georgakoudi, David L. Kaplan, and Aviva J. Symes. Journal of Neuroscience Research (2023).
- 3D biocomposite culture enhances differentiation of dopamine-like neurons from SH-SY5Y cells: A model for studying Parkinson’s disease phenotypes
- Nicholas J. Fiore, Jackson D. Tamer-Mahoney, Afshin Beheshti, Thomas J.F. Nieland, and David L. Kaplan. Biomaterials (2022).
- Potential Involvement of Varicella Zoster Virus in Alzheimer’s Disease via Reactivation of Quiescent Herpes Simplex Virus Type 1
- Dana M. Cairns, Ruth F. Itzhaki, and David L. Kaplan. Journal of Alzheimer’s Disease (2022).
- To see a full list of INSciDE publications, click here.