INSciDE Director David Kaplan elected to National Academy of Engineering
David Kaplan, the Stern Family Professor of Engineering, a Distinguished Professor, and chair of the Department of Biomedical Engineering, has been elected to the National Academy of Engineering in recognition of his contributions to silk-based materials for tissue engineering and regenerative medicine. Election to the National Academies is one of the foremost professional recognitions available to engineers, scientists, and medical experts.
INSciDE team members receive NIH grant to study the role of different cell types and mutations in Alzheimer’s disease
A team of Tufts researchers from the School of Medicine and the School of Engineering has received a five-year, $5 million grant from the National Institute on Aging, part of the National Institutes of Health, to study the role of different cell types and mutations in AD. They will use a unique bioengineered “mini brain” that realistically simulates the human brain environment for years.
Latest INSciDE Research Published in Scientific Journals
Several papers on INSciDE research were recently published in Advanced Functional Materials, Science Advances, Advanced Healthcare Materials, iScience, Macromolecular Bioscience, Neuroscience Letters, and STAR Protocols. These papers include the latest advances in utilizing our 3D bioengineered brain-like tissues as models for studying neuronal networks, cortical impact, and neurodegenerative disease. To read the papers, click on the links below:
- Learning and synaptic plasticity in 3D bioengineered neural tissues
- Nicolas Rouleau, Dana M. Cairns, William Rusk, Michael Levin, and David L. Kaplan. Neuroscience Letters (2021).
- Integrated functional neuronal network analysis of 3D silk-collagen scaffold-based mouse cortical culture.
- Yu-Ting L. Dingle, Mattia Bonzanni, Volha Liaudanskaya, Thomas J.F. Nieland, and David L. Kaplan. STAR Protocols (2021).
- Innovations in 3D tissue models of human brain physiology and diseases.
- Michael L. Lovett, Thomas J.F. Nieland, Yu-Ting L. Dingle, and David L. Kaplan. Advanced Functional Materials (2020).
- Functional characterization of three-dimensional cortical cultures for in vitro modeling of brain networks.
- Yu-Ting L. Dingle, Volha Liaudanskaya, Liam T. Finnegan, Kyler C. Berlind, Craig Mizzoni, Irene Georgakoudi, Thomas J.F. Nieland, and David L. Kaplan. iScience (2020).
- Modeling Controlled Cortical Impact Injury in 3D Brain-Like Tissue Cultures
- Volha Liaudanskaya, Joon Yong Chung, Craig Mizzoni, Nicolas Rouleau, Alexander N. Berk, Limin Wu, Julia A. Turner, Irene Georgakoudi, Michael J. Whalen, Thomas J.F. Nieland, and David L. Kaplan. Advanced Healthcare Materials (2020).
- A 3D human brain-like tissue model of herpes-induced Alzheimer’s disease
- Dana M. Cairns, Nicolas Rouleau, Rachael N. Parker, Katherine G. Walsh, Lee Gehrke, and David L. Kaplan. Science Advances (2020).
- A Long-Living Bioengineered Neural Tissue Platform to Study Neurodegeneration
- Nicolas Rouleau, William L. Cantley, Volha Liaudanskaya, Alexander Berk, Chuang Du, William Rusk, Emily Peirent, Cole Koester, Thomas J.F. Nieland, and David L. Kaplan. Macromolecular Bioscience (2020).
- To see a full list of INSciDE publications, click here.