Tufts Researchers Publish Groundbreaking Study on Bioactive Restorative Material for Non-Carious Cervical Lesions
Boston, MA — A research team from Tufts University School of Dental Medicine, in collaboration with international colleagues, has published a significant clinical study in the Dentistry Journal highlighting the clinical advantages of surface pre-reacted glass-ionomer (S-PRG) filler in resin composites for the restoration of non-carious cervical lesions (NCCLs).
The study, titled “Resin Composite Surface Pre-Reacted Glass-Ionomer (S-PRG) Filler for Non-Carious Cervical Lesions: A Double-Blinded, Randomized, Split-Mouth Clinical Trial,” was co-authored by Dr. Adam Lowenstein, Dr. Carlos Fernando Mourão, Dr. Mabi L. Singh, Dr. Sarah E. Pagni, Dr. Ronald D. Perry, and Dr. Gerard Kugel.
NCCLs, caused by factors such as abrasion, erosion, and occlusal stress, are challenging to treat due to their multifactorial origin and difficulty maintaining long-term adhesion. This randomized, double-blinded, split-mouth clinical trial investigates the role of S-PRG filler in improving clinical outcomes for these restorations.
Key Findings:
- S-PRG fillers were associated with improved marginal integrity and reduced post-operative sensitivity.
- The material demonstrated bioactive properties, including fluoride release and potential anti-demineralization effects.
- These results suggest enhanced restorative longevity and greater patient satisfaction.
“Our findings support the growing body of evidence that bioactive materials can play a significant role in improving clinical success rates in restorative dentistry,” said Dr. Ronald D. Perry, Professor and Director of the International Dental Program at Tufts.
The study underscores the importance of continued innovation in dental biomaterials and reflects Tufts’ ongoing commitment to advancing evidence-based care and translational research in the dental sciences.
The full article is available at: