Publications

17

Lahiri, Priyanka, Martin, Meghan S., Lino, Briana R., Scheck, Rebecca A., and Van Deventer, James A.* Dual Noncanonical Amino Acid Incorporation Enabling Chemoselective Protein Modification at Two Distinct Sites in Yeast. Biochemistry (2023) 62 (14), pp. 2098–2114 https://doi.org/10.1021/acs.biochem.2c00711

Dual Noncanonical Amino Acid Incorporation Enabling Chemoselective Protein Modification at Two Distinct Sites in Yeast

16

Gao, Qingzeng, Jacob-Dolan, Jeremiah W., and Scheck, Rebecca A.. Parkinsonism-Associated Protein DJ-1 Is an Antagonist, Not an Eraser, for Protein Glycation. Biochemistry (2023) 62 (6), pp. 1181–1190 https://doi.org/10.1021/acs.biochem.3c00028

Parkinsonism-Associated Protein DJ-1 Is an Antagonist, Not an Eraser, for Protein Glycation

15

Zhang, Mengyun.†, McEwen, Joseph M.†, Sjoblom, Nicole M., Kotewicz, Kristin M., Isberg, Ralph R.* and Scheck, Rebecca A.*. Members of the Legionella pneumophila Sde Family Target Tyrosine Residues for Phosphoribosyl-Linked Ubiquitination. RSC Chemical Biology (2021) 2 pp. 1509-1519. DOI https://doi.org/10.1039/D1CB00088H †equal contribution, *co-corresponding

Members of the Legionella pneumophila Sde Family Target Tyrosine Residues for Phosphoribosyl Linked Ubiquitination

14

McEwen, Joseph M., Fraser, Sasha, Sosa Guir, Alexxandra, Dave, Jaydev, and Scheck, Rebecca A. Synergistic sequence contributions bias glycation outcomes Nature Communications (2021) 12, 3316 pp. 1-10. https://doi.org/10.1038/s41467-021-23625-8

Synergistic sequence contributions bias glycation outcomes

13

Chambers, Kaitlin A. and Scheck, Rebecca A. Bacterial virulence mediated by orthogonal post-translational modification. Nature Chemical Biology (2020) 16, pp 1043–1051. https://doi.org/10.1038/s41589-020-0638-2

Bacterial virulence mediated by orthogonal post-translational modification

12

Chambers, Kaitlin A., Abularrage, Nile S., Hill, Caitlin J., Khan, Imran H., and Scheck, Rebecca A. A chemical probe for dehydrobutyrine. Angewandte Chemie International Edition (2020) 59 (19), pp 7350-7355. https://doi.org/10.1002/anie.202003631

A chemical probe for dehydrobutyrine

11

Sjoblom, Nicole M., Kelsey, Maxfield M.G., and Scheck, Rebecca A. A systematic study of protein glycation. Angewandte Chemie International Edition (2018) 57 (49), pp 16077-1608. https://doi.org/10.1002/anie.201810037

A systematic study of protein glycation

10

Chambers, Kaitlin A., Abularrage, Nile S., and Scheck, Rebecca A. Selectivity within a family of bacterial phosphothreonine lyases. Biochemistry (2018) 57 (26), pp 3790–3796. https://doi.org/10.1021/acs.biochem.8b00534

Selectivity within a family of bacterial phosphothreonine lyases

9

Kotewicz, Kristin, M., Ramabhadran, Vinay, Sjoblom, Nicole, Haenssler, Eva, Zhang,Mengyung, Scheck, Rebecca A.,and Isberg, Ralph R. A single Legionella effector catalyzes a multistep ubiquitination pathway to rearrange tubular endoplasmic reticulum for replication. Cell Host Microbe (2017) 21(2), pp 169-181. https://doi.org/10.1016/j.chom.2016.12.007

A single Legionella effector catalyzes a multistep ubiquitination pathway to rearrange tubular endoplasmic reticulum for replication

Prior to Tufts

8

Doerner, Amy E., Scheck, Rebecca A., Schepartz, Alanna. Growth factor identity is encoded by discrete coiled-coil rotamers in the EGFR juxtamembrane region. Chemistry & Biology (2015) 22(6), pp 776-784.

Growth factor identity is encoded by discrete coiled-coil rotamers in the EGFR juxtamembrane region

7

Scheck, Rebecca A., Lowder, Melissa A., Appelbaum, Jacob S., and Schepartz, Alanna. Bipartite tetracysteine display reveals allosteric control of ligand-specific EGFR activation. ACS Chemical Biology (2012) 7(8), pp 1367-1376.

Bipartite tetracysteine display reveals allosteric control of ligand-specific EGFR activation

6

Scheck, Rebecca A. and Schepartz, Alanna. Surveying protein structure and function using bis-arsenical small molecules. Accounts of Chemical Research (2011) 44(9), pp 654–665.

Surveying protein structure and function using bis-arsenical small molecules

5

Witus, Leah S., Moore, Troy., Thuronyi, Benjamin W., Esser-Kahn, Aaron P., Scheck, Rebecca A., Iavarone, Anthony, T., and Francis, Matthew B. Identification of highly reactive sequences for PLP-mediated bioconjugation using a combinatorial peptide library. Journal of the American Chemical Society (2010) 132(47), pp 16812–16817.

Identification of highly reactive sequences for PLP-mediated bioconjugation using a combinatorial peptide library

4

Scheck, Rebecca A., Dedeo, Michel, T., Iavarone, Anthony, T., and Francis, Matthew B. Optimization of a biomimetic transamination reaction. Journal of the American Chemical Society (2008), 130(35), pp 11762–11770.

Optimization of a biomimetic transamination reaction

3

Scheck, Rebecca A., Francis, Matthew B. Regioselective labeling of antibodies through N-terminal transamination. ACS Chemical Biology (2007), 2(4), pp 247-251.

Regioselective labeling of antibodies through N-terminal transamination

2

Gilmore, Joshua M.†, Scheck, Rebecca A.†, Joshi, Neel S., Francis, Matthew B. N-terminal protein modification through a biomimetic transamination reaction. Angewandte Chemie-International Edition (2006), 45(32), pp 5307-5311. †equal contribution

N-terminal protein modification through a biomimetic transamination reaction

1

Tulevski, George S., Miao, Qian., Fukuto, Masafumi, Abram, Rebecca, Ocko, Benjamin, Pindak, Ronald, Steigerwald, Michael L., Kagan, Cherle R., Nuckolls, Colin. Attaching organic semiconductors to gate oxides: In situ assembly of monolayer field effect transistors. Journal of the American Chemical Society (2004), 126(46), pp 15048-15050.

Attaching organic semiconductors to gate oxides: In situ assembly of monolayer field effect transistors