The Moscow State Institute of International Relations (MGIMO University) of the Russian Federation Ministry of Foreign Affairs and The Fletcher School of Law and Diplomacy at Tufts University will hold their fourth joint conference on Grand Challenges in Russia-U.S. Relations on April 1-2, 2019 on the Tufts University campus. The conference will focus on empirical, theoretical, normative, and legal questions related to the principle of non-interference in domestic affairs; Russia’s understanding of alliances, partnerships, and coalitions; and Russia-U.S. relations in the evolving world order. Attendance is by registration only on Eventbrite. The event is being organized by the two universities in partnership with the Alexander Gorchakov Public Diplomacy Fund and Carnegie Corporation of New York. The previous MGIMO-Fletcher conferences on U.S.-Russia relations held in November 2017, May 2018, and March 2019 provided an opportunity to clarify disagreements and potential areas of cooperation between the United States and Russia. The goals of the joint MGIMO-Fletcher conference series are to examine both the depth and scope of disagreements between the United States and Russia, assess the potential for bilateral cooperation in the areas of shared interests, educate future U.S. and Russian decision-makers, and foster mutual understanding between Russian and American scholars and practitioners. We are thankful for the support of our sponsors, partners, and volunteers. When tweeting about the event, please use #FletcherMGIMO.